Researchers from Kumamoto University have identified a liver-derived protein, serine protease inhibitor A1 (SerpinA1), as a key regulator in combating obesity and enhancing glucose metabolism. This study, published in Nature Communications, sheds light on how activating brown adipose tissue (BAT) could pave the way for innovative treatments for diabetes and metabolic disorders.
Tracking the metabolic origins of cancer from a mosaic of cells
Yale researchers are sifting through a mosaic of cells in a living animal—both normal cells and mutated cells—to better understand how cancer grabs a foothold. But they’re starting by studying tolerance.
End-of-life care can be more aggressive for cancer patients with defibrillators
Patients with advanced cancer who also had cardiac defibrillators were more likely than those without these implants to receive aggressive end-of-life care, a team led by UT Southwestern Medical Center researchers found in a new study. The findings, published in Cancer, could help physicians guide patients in this growing population toward care that better matches their goals.
Hospitals’ AI tools under scrutiny for accuracy and bias
New research from the University of Minnesota School of Public Health sheds light on how hospitals in the U.S. are using artificial intelligence to perform daily tasks.
Blood, urine and other bodily fluids: How your leftover pathology samples can be used for medical research
A doctor’s visit often ends with you leaving with a pathology request form in hand. The request form soon has you filling a sample pot, having blood drawn, or perhaps even a tissue biopsy taken.
Wellness Inventory receives empirically valid ‘gold star’: Researcher discusses assessment tool in Q&A
Margaret “Peggy” Swarbrick has spent her career helping people help themselves.
Childhood maltreatment may alter sperm, affecting future generations’ brain development
Childhood stress can impact the epigenetic profile of sperm. These results may also have practical implications for future generations through epigenetic inheritance, as many of the observed epigenetic associations are related to brain development.
Calming chaotic waves with small electrical intervention: Researchers develop technique to stop irregular heartbeats
Researchers from Durham University have made an exciting discovery that could improve how doctors treat dangerous heart rhythms, like those seen in cardiac arrest.
Novel brain mechanism links neurotransmitters to circadian gene expression
A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.
Study sheds light on depression in community-dwelling older adults
Marked variation in the prevalence of depression was found in a multisite sample of community-dwelling older adults in the United States, reports a study by Columbia University Mailman School of Public Health. Until now, few studies have examined the frequency of depression in community-dwelling older adults in the U.S. The study is published in the Journal of American Geriatrics Society.