Pregnancy may reduce long COVID risk

Pregnancy may offer some protection from developing long COVID, found a new study led by Weill Cornell Medicine, University of Rochester Medical Center, University of Utah Health and Louisiana Public Health Institute. Previous research has mostly focused on non-pregnant adults affected by long COVID— a condition lasting for months after a person recovers from SARS-CoV-2 infection.

Preventable pediatric cancer mortality surges in areas of armed conflict, exceeding rates in non-conflict regions

More than half of all pediatric cancer deaths worldwide occur in regions of armed conflict, according to a new study led by investigators from St. Jude Children’s Research Hospital, Duke University and other collaborators. The study demonstrated that pediatric cancer diagnoses and mortality are significantly impacted in areas of armed conflict and documented the significant contribution these troubled areas make to the global burden of childhood cancer.

IL-7 treatment shows promise in reducing lethal secondary infections in critically ill COVID-19 patients

A new study published in JCI Insight suggests that interleukin-7 (IL-7), a key immune-boosting cytokine, may help critically ill COVID-19 patients by reducing life-threatening secondary infections. Led by Richard S. Hotchkiss, MD, professor of anesthesiology, medicine, surgery, and developmental biology at WashU Medicine, the study highlights IL-7’s ability to enhance immune recovery without triggering harmful inflammation.

People with heart failure can safely drink fluids without restrictions: Clinical trial challenges common advice

People with heart failure are often advised to limit their fluid intake. However, a large study led by Radboud University Medical Center now shows that this practice does not provide any health benefits. Researchers writing in Nature Medicine found that it is safe when patients with heart failure regulate their own fluid intake.

Omega-3s have potential to counteract THC effects on fetal development, study finds

Previous studies show exposure to Tetrahydrocannabinol (THC)—the main psychoactive component in cannabis—while in utero can lead to lower birth weight and potential heart complications in newborn animal offspring. For the first time, researchers from Western’s Schulich School of Medicine & Dentistry have found a potential way to prevent those effects.

An immune cell may explain how maternal inflammation causes neurodevelopmental disorder

A research group led by Nagoya University Graduate School of Medicine in Japan has uncovered a potential mechanism linking maternal inflammation to delayed neurodevelopment in infants. The research suggests the role of CD11c-positive microglia—immune cells in the brain crucial for myelination—during infant brain development. The results, published in Communications Biology, suggest new strategies to mitigate the long-term neurodevelopmental effects of maternal inflammation.

Omega-6 fatty acid promotes the growth of an aggressive type of breast cancer, study finds

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat “triple negative” breast cancer subtype, according to a preclinical study led by Weill Cornell Medicine investigators. The discovery could lead to new dietary and pharmaceutical strategies against breast and other cancers.