All posts by : Felistas

In a large-animal model study, researchers have found that heart attack recovery is aided by the injection of heart muscle cell spheroids derived from human-induced pluripotent stem cells (hiPSCs), that overexpress cyclin D2 and are knocked out for human leukocyte antigen classes I and II.

A global study reveals a disturbing rise in early-onset gastric cancer, a disease once predominantly affecting older adults but now increasingly impacting younger populations. This shift in disease patterns, uncovered through a 15-year analysis, calls for urgent reevaluation of global health strategies and targeted interventions.

A recent study published in Synthese challenges the default collection and reliance on ethno-racial data in biomedical research, arguing that these practices often lack scientific or ethical justification. The paper critically examines the widely accepted “fair subject selection” requirement, which mandates proportional representation of racial groups in clinical trials, and suggests that this approach might inadvertently perpetuate scientific inaccuracies and social stereotypes.

The typical cost of developing new medications may not be as high as generally believed, with a few ultra-costly medications skewing public discussions about the cost of pharmaceutical research and development, according to a new RAND study.

A study led by the University of California, Irvine has found cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, not to be associated with an increased risk of such harm in individuals 90 and older.

A new type of bioengineered blood vessel has shown strong results in treating severe vascular injuries, potentially offering vascular surgeons a better alternative to synthetic grafts when patients’ veins aren’t suitable for use in repairs.

Mice infected with the bacteria that cause tuberculosis (TB) fared better when treated with an experimental compound that modulates immune responses than untreated mice did, according to a study led by Christina Stallings, a professor of molecular microbiology at Washington University in St. Louis (WashU) Medicine.

A new systematic literature search has identified the highest priority clinical actions aimed at improving post-acute care for non-hospitalized traumatic brain injury (TBI).

A study published in Human Gene Therapy has involved the generation of a human monoclonal antibody (mAb) directed against human eosinophils. The heavy and light chains of that fully human anti-human eosinophil mAb were delivered via an adeno-associated virus (AAV)-based gene therapy to immunodeficient mice, where they suppressed levels of human eosinophils in vivo.

Researchers at UT Southwestern Medical Center have discovered sex-specific differences in how fat accumulates in muscle and bone, uncovering patterns that could inform new approaches to treating age-related diseases.