Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a study published in the open-access journal PLOS Biology by Sheng Huang and Stephan Sigrist from Freie Universität Berlin, Germany, and colleagues. The paradox of enhanced memory despite sleep loss could be explained by protein kinase A (PKA) signaling in the mushroom body of the fly brain.
Disruptions in amino acid, lipid metabolism may signal tardive dyskinesia, study suggests
Disruptions in amino acid and lipid metabolism may be biomarkers of tardive dyskinesia (TD), according to a study published online in Schizophrenia Bulletin.
DeepCeres: AI-driven software redefines cerebellum research with detailed imaging
A team of researchers from the Universitat Politècnica de València (UPV) and the French National Center for Scientific Research (CNRS) has developed the world’s most advanced software to study the human cerebellum using high-resolution NMR images.
JAK inhibitor combo therapy shows promise for myelofibrosis treatment in phase 3 trial
Researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai have demonstrated the potential for a new combination therapy to improve outcomes for patients with myelofibrosis, a rare and aggressive blood cancer.
A new form of immune memory: Macrophages can adapt to past infections
Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit for giving the human immune system a memory. Now, researchers at the University of Chicago Pritzker School of Molecular Engineering have discovered a new form of immune memory.
Cell atlas of the endometrium in women with PCOS may lead to better treatment
Women with polycystic ovary syndrome (PCOS) find it harder to get pregnant, have more frequent miscarriages and have a higher risk of developing endometrial cancer.
Chronic jet lag disrupts metabolism differently in male and female mice, study finds
Jet lag is one of the worst parts of long-distance traveling or shift work—it makes us tired and cranky, and also plays havoc with our metabolism (and therefore our weight). Now, new research on mice suggests that the way jet lag impacts our metabolism may depend on our sex.
5 years on, true counts of COVID-19 deaths remain elusive, and research is hobbled by lack of data
In the early days of the COVID-19 pandemic, researchers struggled to grasp the rate of the virus’s spread and the number of related deaths. While hospitals tracked cases and deaths within their walls, the broader picture of mortality across communities remained frustratingly incomplete.
Trump administration may cut CDC’s HIV prevention division
The Trump administration is weighing elimination of the U.S. Centers for Disease Control and Prevention’s (CDC) Division on HIV Prevention, sparking concerns among public health experts.
FDA increases testing for heavy metals in baby formula
The U.S. Food and Drug Administration (FDA) is stepping up testing for heavy metals in infant formula and reviewing key nutrients required in these products, federal health officials said.