One of Australia’s most common gynecological cancers could be detected sooner and more accurately thanks to a specialized artificial intelligence (AI) model, new research shows.
Research reveals how childhood adversity shapes the brain and behavior
Early-life adversity affects more than half of the world’s children and is a significant risk factor for cognitive and mental health problems later in life. In an extensive and up-to-the-minute review of research in this domain, scholars from the University of California, Irvine illuminate the profound impacts of these adverse childhood experiences on brain development and introduce new paths for understanding and tackling them.
Current antivirals don’t work well against H5N1 avian influenza virus in cows’ milk, scientists find
As the H5N1 avian influenza outbreak continues, scientists are working to better understand the virus’s threat to human health. The virus has been found in dairy cows’ milk and has infected farm workers, prompting scientists at St. Jude Children’s Research Hospital to study potential treatments.
First patient in New York has been cured of sickle cell anemia with advanced treatment
For 21 years, Sebastien Beauzile lived with the chronic pain of sickle cell anemia. Now, thanks to a groundbreaking genetic treatment, he is the first person in New York to be cured of the disease.
FDA warns of rising injuries from misuse of laughing gas
Health officials are warning about a rise in injuries linked to the misuse of nitrous oxide, aka laughing gas.
Novel intercellular mechanisms may inform treatments for congenital spinal defects
Northwestern Medicine investigators have identified novel mechanisms regulating the development of the spinal column during embryonic development, findings that could inform new treatments for congenital scoliosis and other related birth defects, according to a recent study published in Nature Communications.
Understanding dental implant failure: Key risk factors and future directions
Dental implants have revolutionized the treatment of missing teeth, providing a reliable and aesthetically pleasing alternative to traditional dentures and bridges. However, implant failure remains a concern, particularly in the first two years after placement.
Treating chronic inflammatory diseases with JAK inhibitors
Janus kinase (JAK) inhibitors are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn’s disease or ulcerative colitis. Since their approval, the indications for these medical drugs have steadily increased, but recently safety concerns have also been raised.
Chchd10 protein’s regulation of adipose tissue offers new obesity management strategies
Obesity is a global health concern closely linked to a range of metabolic diseases, such as type 2 diabetes and cardiovascular diseases. A research team from the Department of Pharmacology and Pharmacy, LKS Faculty of Medicine at the University of Hong Kong (HKUMed), identified the mitochondria protein Chchd10 as a novel regulator of adipose tissue homeostasis, offering new insights into the management of obesity and its related metabolic disorders. The findings were published in Advanced Science.
Personalized cancer vaccine proves promising in a phase 1 trial
Researchers at the Icahn School of Medicine at Mount Sinai, led by Nina Bhardwaj, MD, Ph.D., Ward-Coleman Chair in Cancer Research and Director of the Vaccine and Cell Therapy Laboratory, have tested a promising new type of personalized multi-peptide neoantigen cancer vaccine, called PGV001, in a small group of patients.