A new study reveals striking international differences in how doctors approach the sensitive issue of tracheostomy invasive ventilation (TIV) for patients with amyotrophic lateral sclerosis (ALS). Cultural norms and health care systems appear to significantly influence physician attitudes and, consequently, patient choices regarding this life-sustaining treatment.
Holiday heart: The overindulgences during festival season that put even healthy people at risk
Festival season can be surprisingly physically demanding. Hours spent standing, walking or dancing can put extra strain on the heart, especially for those with preexisting conditions such as heart disease, high blood pressure or diabetes, explains Gosia Wamil, M.D., Ph.D., a cardiologist at Mayo Clinic Healthcare in London.
Combination therapy found safe and beneficial for acute myeloid leukemia patients with specific genetic profile
A combination therapy that adds a recently approved drug to the current standard of care for newly diagnosed acute myeloid leukemia (AML) showed high rates of complete remission in an early-phase clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and 11 other sites nationwide.
Nonlinear neural network model reveals how fly brains reduce odor complexity
Two RIKEN researchers have used a scheme for simplifying data to mimic how the brain of a fruit fly reduces the complexity of information about smells it perceives. This could also help enhance our understanding of how the human brain processes sensory data.
Eco-friendly coatings boost strength and biocompatibility of titanium dental implants
New research from SUNY Polytechnic Institute introduces an innovative, eco-friendly method to enhance the performance and longevity of titanium-based dental implants, focusing on improving the biocompatibility and mechanical resilience of Ti-6Al-4V alloy implants using hydroxyapatite (HA) coatings derived from biowaste.
Impact of education and social factors in rheumatic and musculoskeletal diseases
Social determinants of health (SDH), such as socioeconomic status and educational background are factors that are increasingly recognized as critical contributors to health outcomes in chronic diseases. Understanding how certain factors impact different rheumatic and musculoskeletal diseases (RMDs) is important, and new research into this for both systemic lupus erythematosus (SLE) and inflammatory arthritis was presented at the EULAR 2025 congress in Barcelona.
Large study finds no significant overall cancer risk increase with JAK inhibitors in RA
Regulatory authorities issued precautionary recommendations following the ORAL Surveillance trial, which demonstrated an elevated risk of cancer with tofacitinib, compared to TNF inhibitors (TNFi).
Microbiota poised for diagnostic and therapeutic roles in clinics within 5–10 years, says expert
Both diagnostic and therapeutic use of the microbiota will become reality within the next 5–10 years. It emerges from an “informative” article published in Cell, written by doctors for doctors, to inform clinicians that a series of valuable diagnostic and therapeutic applications based on the microbiome could be just around the corner and bridge the communication gap between basic researchers and clinicians, which is slowing down their implementation.
Patient classification systems can have negative consequences, especially under scarcity
It is well known that both scarcity of resources and expectations of efficacy influence preferences and decisions in health care. But how do these two factors (scarcity and expectations) affect when both are combined? Why, for example, were specific groups of patients (mainly elderly and disabled) so obviously discriminated against during the COVID-19 pandemic, when medical resources were particularly scarce?
Older adults with dementia misjudge their financial skills, which may make them more vulnerable to fraud
Older adults diagnosed with dementia lose their ability to assess how well they manage their finances, according to a recent study I co-authored in The Gerontologist. In comparison, people of the same age who don’t have dementia are aware of their financial abilities—and this awareness improves over time.