Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center. The results, published in Cancer Discovery, prime the combination strategy for future clinical trials.

Decreased levels of TDP-43 gene may be contributing to neurodegenerative diseases like Alzheimer’s and ALS

In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer’s disease, and the progressive damage to the brain’s frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).

Veep dismisses claims of extending Presidential term through Constitutional Amendments.

VICE President Mutale Nalumango says there are no intentions to extend the President’s term of office through constitutional amendments. Mrs Nalumango said the purpose of amending the Constitution is to improve and enhance citizen participation in governance. She made the remarks in Parliament while responding to a question from Mkaika Member of Parliament Peter Phiri, […]

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