Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center. The results, published in Cancer Discovery, prime the combination strategy for future clinical trials.
Decreased levels of TDP-43 gene may be contributing to neurodegenerative diseases like Alzheimer’s and ALS
In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer’s disease, and the progressive damage to the brain’s frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).
Photoacoustic imaging reveals new insights into how the brain learns new information
Wayne State University researchers are using photoacoustic imaging to observe brain activity and, in the process, discovering more about how it responds to different types of learning and experiences.
Blood tests suggest that social disadvantage can accelerate aging and increase disease risk
People with favorable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological aging than peers of the same age, finds a new study led by University College London (UCL) researchers.
How to prevent chronic inflammation from zombie-like cells that accumulate with age
In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.
Medical imaging experts better at solving optical illusions—study shows training can improve visual perception
Medical imaging experts are adept at solving common optical illusions, according to research from four UK universities, including the University of East Anglia.
Study highlights that less than 1% of people with firearm access engage in defensive use in any given year
Those with access to firearms rarely use their weapons to defend themselves, and instead are far more likely to be exposed to gun violence in other ways, according to a Rutgers Health study.
Study reveals new insights into the origins of ovarian cancer
Researchers at the University of Pittsburgh have identified a novel trigger for a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.
Two brain areas compete for control of memories, optogenetics study shows
Researchers at Ruhr University Bochum, Germany, have studied the impact of two brain areas on the nature of memory content. The team from the Department of Neurophysiology showed in rats how the so-called locus coeruleus and the ventral tegmental area permanently alter brain activity in the hippocampus region, which is crucial for the formation of memory.
Veep dismisses claims of extending Presidential term through Constitutional Amendments.
VICE President Mutale Nalumango says there are no intentions to extend the President’s term of office through constitutional amendments. Mrs Nalumango said the purpose of amending the Constitution is to improve and enhance citizen participation in governance. She made the remarks in Parliament while responding to a question from Mkaika Member of Parliament Peter Phiri, […]
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