Chronic rhinosinusitis with nasal polyps presents a substantial clinical burden, affecting nasal airflow, olfactory function, and quality of life. Epithelial barrier dysfunction and type 2 inflammatory responses drive disease progression. Treatments such as intranasal glucocorticoids and sinus surgery provide limited long-term relief and fail to address the underlying inflammatory mechanisms.
Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic cancer respond to immunotherapies. The findings, which were recently published in the journal Cancer Research Communications, reinforce the need to include racially diverse participants in clinical studies.
An international group of researchers has identified an important mechanism that enables stem cells to evade immune rejection. Their research, published in Nature, sheds light on how these specialized cells create an “immune-privileged” environment—areas in the body where stem cells survive and function without being attacked by the immune system. The team was led by Kazuhiro Furuhashi (Nagoya University and Columbia University) and Joji Fujisaki (Harvard University and Columbia University).
Diabetes affects more than 1 in 10 adults worldwide and has been accompanied by an increase in vision-threatening diabetic retinal disease (DRD).
Researchers from Columbia University and the German Cancer Center have found that stellate cells—star-shaped liver cells long known as the main perpetrators of liver fibrosis—have a commanding role in protecting and sustaining the liver’s organization and function before they go rogue and cause liver damage.
Terpenes from the Cannabis sativa plant may be a viable medication for fibromyalgia and post-surgical pain relief, according to University of Arizona Health Sciences research published in Pharmacological Reports.
Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma—the most common type of malignant brain tumor in children—and potentially sparing young patients from unnecessary treatments and their harmful long-term side effects.
For college athletes with concussion, brain changes may remain visible in brain scans up to a year after they are cleared to return to play, according to a study published online in Neurology.
The American Academy of Neurology (AAN), the American Epilepsy Society (AES) and the Epilepsy Foundation of America (EFA) have issued a consensus position statement on seizures, driver licensure and medical reporting.
Sam Srisatta, a 20-year-old Florida college student, spent a month living inside a government hospital here last fall, playing video games and allowing scientists to document every morsel of food that went into his mouth.