Scientists identify lncRNA as potential biomarker and therapeutic target for hepatocellular carcinoma

Hepatocellular carcinoma (HCC), the third leading cause of cancer-related deaths worldwide, remains one of the most aggressive malignancies. In a recent study published in Nature Communications, researchers led by Profs. Yang Pengyuan and Chen Runsheng from the Institute of Biophysics of the Chinese Academy of Sciences have uncovered a novel mechanism by which tumor-derived long noncoding RNA (lncRNA) suppresses anti-tumor immunity, providing new insights into the role of extracellular vesicles (EVs) in HCC progression.