What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients’ cells? Genetic screening may have unlocked a path for treating the severe inflammation associated with many immune diseases by regulating one protein’s role in helping another protein control cell acidity, according to new research published in Cell by a team from the Perelman School of Medicine at the University of Pennsylvania.
Researchers uncover hidden barrier to spinal cord injury recovery
New research from the University of Kentucky has earned a spot on the cover of the Journal of Neuroscience, highlighting a major challenge in spinal cord injury recovery.
Blood test shows promise for early detection of dementia in people with a certain sleep disorder
For people with a certain sleep disorder, a simple blood test could help predict the development of dementia years before symptoms appear, a new study indicates.
How the pandemic’s narratives are still unfolding, five years on
Do you clearly remember the choices you made a few years ago during the early days of the COVID pandemic? Did you painstakingly wipe down your groceries before putting them away, quarantine your mail three days before opening it, or hoard toilet paper while others were unable to find a roll? Is the nasty argument with your brother-in-law over children’s COVID vaccination fully forgotten, or does a twinge of annoyance still flicker when he speaks at family gatherings?
How proteins guide plasma cells to bone marrow for long-term immunity
Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections. Now, researchers from Japan report that antibody-producing cells are destined for longevity from the moment they are born.
Nwd1 gene deletion triggers MASH-like pathology in mice
Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns. It is prevalent in 30% of the population worldwide and poses a risk of advancing to cirrhosis and liver cancer.
Washington lawmakers push to expand mental health insurance coverage
When people seek mental health treatment in Washington, insurance companies are supposed to cover that care just like they would physical ailments.
Measles ‘is not a benign disease’
Northwestern University infectious disease expert Dr. Tina Tan said it’s likely the measles outbreak in West Texas and on the border of New Mexico will continue to spread due to a large unvaccinated population that is highly susceptible to “one of the most contagious viruses.”
New technique reveals how axon swellings could be treated in Alzheimer’s disease
For decades, scientists have focused on amyloid plaques—abnormal clumps of misfolded proteins that accumulate between neurons—as a therapeutic target for Alzheimer’s disease. But anti-amyloid therapies haven’t made strong headway in treating the devastating condition.
Supportive workplace culture advances implementation of lifestyle medicine in health systems, study finds
Workplace culture plays an integral role in the successful adoption of lifestyle medicine programming within health systems, according to a new study published in BMJ Open.