Bladder macrophages form immune barrier against bloodstream infections, study finds

A research team led by Prof. Zeng Zhutian from the University of Science and Technology of China (USTC) has identified and named a novel population of bladder-resident macrophages, termed suburothelial perivascular macrophages (suPVMs), which can prevent hematogenous dissemination of uropathogens by releasing macrophage extracellular traps (METs). This finding has been published in Immunity.

Natural defense mechanism may help slow down tumor cell metastasis

Researchers at Karolinska Institutet, led by Dr. Helin Norberg and Dr. Erik Norberg, have identified a previously unknown mechanism that affects the ability of cancer cells to spread in the body. The study, published in EMBO Molecular Medicine, shows that a process called chaperone-mediated autophagy (CMA) may function as a natural defense mechanism against metastases.