How toxic are softgel capsules?

Softgel capsules—the smooth, easy-to-swallow form of many medications and supplements—are increasingly popular for delivering everything from vitamins to omega-3s. These capsules, made of a liquid center inside a soft, flexible shell, offer convenience and effectiveness. But they’ve also come under growing scrutiny for one surprising reason: plasticizers.

Could the same technology that enables targeted immunotherapy for cancer be used to tackle Alzheimer’s?

Inspired by advances in cancer therapy, a team at the Buck Institute has engineered immune cells equipped with specialized targeting devices called chimeric antigen receptors (CARs) that can distinguish and respond to tau tangles and various forms of toxic amyloid plaques, both of which are implicated in Alzheimer’s disease pathology.