Cart is empty Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The study, published in the Journal of Clinical Investigation, shows that the growth factor PDGF-CC and its receptor PDGFRα play a crucial role in scar formation in the brain after an ischemic stroke.
Molecular glues can shield insulin-producing cells from diabetes-related damage
Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity—a harmful condition linked to the progression of type 2 diabetes (T2D). These findings, published on March 2, 2025 in Nature Communications, could lead to promising treatments targeting beta cell dysfunction.
Indigenous Australians bear disproportionate burden of allergy-related illness, finds study
Researchers at The University of Queensland have found First Nations people are twice as likely to present at hospital with asthma and other allergy-related illnesses, compared to other Australians.
New consensus report on anaphylaxis: A major advancement in allergy care
A groundbreaking consensus report on anaphylaxis—the severe reaction some people experience from bee stings, peanut butter exposures, medications, and the like—has been released by the Global Allergy and Asthma Excellence Network (GA2LEN) and recently published in The Journal of Allergy and Clinical Immunology.
Scientists identify neural mechanism of leptin resistance in obesity—and how to reverse it
Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of cases share one thing in common: leptin resistance.
Study reveals four novel genes required for male fertility in mice
The pioneering research of UC Santa Cruz’s Upasna Sharma to determine how a father’s life experiences and environment can influence the health and well-being of his children moves forward with the recent discovery of four genes required for male fertility and the creation of specific RNA molecules in sperm.
Out-of-balance gut bacteria are linked to multiple sclerosis—the ratio can predict severity of disease
Multiple sclerosis is a disease that results when the immune system mistakenly attacks the brain and spinal cord. It affects nearly 1 million people in the U.S. and over 2.8 million worldwide. While genetics play a role in the risk of developing multiple sclerosis, environmental factors such as diet, infectious disease and gut health are major contributors.
How the brain distinguishes between pain and itch
A research team led by Kaang Bong-Kiun, director of the Center for Cognition and Sociality within the Institute for Basic Science (IBS), and Ko Hyoung-Gon, professor at Kyung Hee University College of Dentistry, have uncovered the neural mechanisms underlying the processing of pain and itch in the anterior cingulate cortex (ACC).
Facial thread lifting: Plastic surgeons discuss complications, causes and prevention
A technique called facial thread lifting has become increasingly popular as a minimally invasive alternative to surgical facelifting. A report in The Journal of Craniofacial Surgery highlights anatomy-based techniques designed to reduce the risk of complications and side effects of facial thread lifting.
Police study shows why some are more susceptible to developing PTSD symptoms than others
People with a more active amygdala (an area in the brain involved in processing information relevant to threats) are more likely to develop PTSD symptoms after experiencing trauma than people with a calmer amygdala. This is evident from research on police officers by neuroscientist Linda de Voogd together with a team of scientists led by Karin Roelofs of Radboud University.