Test identifies prior infection by Zika virus and all four dengue virus serotypes

Brazilian researchers have developed a simple test that almost instantly tells whether a person has been exposed to any of the four dengue virus serotypes, as well as Zika virus. The test is an enzyme immunoassay similar to ELISA, a platform widely used in laboratory testing throughout Brazil. The technology can easily be adapted for use in automated systems and rapid point-of-care tests.

High-throughput sequencing genetic testing identifies 25% more rare disease risks

Rare diseases (RD) are more common than you might think. For every 20 people you know, one is likely affected by a rare disease. Of the 7,000 known RD conditions, 80% have a genetic origin, yet over 95% remain incurable. Preventive genetic testing offers families a powerful tool to make informed reproductive choices, potentially preventing these diseases before they manifest.

Physical activity linked to lower risk of dementia, sleep disorders, other diseases

People who get moderate to vigorous physical activity may be less likely to develop dementia, stroke, anxiety, depression, and sleep disorders, according to a preliminary study released today, February 27, 2025, that will be presented at the American Academy of Neurology’s 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

Medicaid extension policies covering all immigrants found to reduce inequities in postpartum insurance coverage

A new study at Columbia University Mailman School of Public Health reveals that Medicaid extension policies, which cover all immigrants in the post-COVID era, have led to a notable reduction in postpartum uninsurance, particularly in New York City. However, the study highlights that awareness gaps may have hindered the full benefit for Hispanic immigrants. The results are published in the American Journal of Public Health.

How the nervous system modulates pain signals: New finding reveals a novel target for future therapies

Sensory neurons that respond to temperature, touch and pain have ways of adapting to repeated stimuli that can change how a body experiences those sensations. In a recent paper published in the Proceedings of the National Academy of Sciences, Thomas Jefferson University researchers describe a specific molecular change that accounts for this altered neuronal activity and, in turn, the strength of pain sensation.

Kidney cancer: Understanding what a renal cell carcinoma diagnosis means

Renal cell carcinoma is the most common form of kidney cancer. It can take time to fully process a diagnosis and what, exactly, it may mean. Developing a good understanding of your disease—and especially the diagnostic process—can help you set realistic expectations and take an active part in your treatment plan, says Bradley Leibovich, M.D., a urologist at Mayo Clinic.

New 4D brain map reveals potential early warning signs of multiple sclerosis

Using an animal model of multiple sclerosis (MS), researchers at the National Institutes of Health (NIH) have created a four-dimensional brain map that reveals how lesions similar to those seen in human MS form. These findings, published in Science, provide a window into the early disease state and could help identify potential targets for MS treatments and brain tissue repair.