A genomics approach to metabolism reveals how reactions flow

Two papers published today in the journal Nature describe a significant advance in understanding the complex functions of the metabolic network. The research is from the lab of Marian Walhout, Ph.D., the Maroun Semaan Chair in Biomedical Research and chair and professor of systems biology, who has been engaged with fundamental questions of metabolism for more than a decade.

Innovative CT scan technique could improve prognosis and treatments for head and neck cancers

Cancers occurring in the mouth, nose, and throat are on the rise in the U.S., especially in younger people. About 60,000 new cases are diagnosed every year, with one in five cases occurring in people younger than 55, according to the American Cancer Society. A new study provides insights that may eventually help oncologists better predict how the disease will respond to certain therapies, leading to improved survival outcomes for patients.

A new path to recovery: Scientists uncover key brain circuit in the fight against cocaine use disorder

Imagine a future where the grip of cocaine use disorder can be loosened, where cravings fade, and the risk of relapse diminishes. A new study published in Science Advances, led by Penn Nursing’s Heath Schmidt, Ph.D., brings this vision closer to reality. The research has identified a critical brain circuit that plays a pivotal role in regulating cocaine-seeking behavior.