New study highlights need for better care to prevent lung problems after abdominal surgery

A new study, published today in The Lancet Respiratory Medicine, has tested whether a set of interventions to keep lungs expanded before, during, and after abdominal surgery could lower the risk of serious breathing problems in patients compared to the usual care at 17 academic hospitals in the U.S. The research has determined that these interventions for open abdominal surgery do not result in less severe breathing problems as compared to the usual care in those hospitals.

Novel tool enhances study of PTEN gene linked to cancer and autism

A novel scientific method developed at Tel Aviv University promises to accelerate our understanding of the gene PTEN, a key player in cellular growth. This breakthrough will help scientists better understand how cells grow and divide, potentially leading to advancements in the treatment of a range of conditions, including developmental disorders and various forms of cancer.

New target points to combination therapy for thwarting multidrug resistance in cancer treatment

Multidrug resistance in cancer can be overcome by combining a drug that blocks a key enzyme with another anticancer drug, according to a study in preclinical models led by researchers at UT Southwestern Medical Center. The findings, published in Science Advances, could have implications for patients with certain cancers that have KRAS-G12C mutations after resistance to drug therapy develops.