The ‘lab-leak origin’ of COVID-19: Fact or fiction?

In a January 24 interview with the far-right-wing outlet Breitbart News, newly appointed CIA director John Ratcliffe stated that assessing intelligence on a potential Wuhan lab leak was a top priority. The following day, The New York Times reported that the agency had shifted from an undecided stance to favoring a possible Chinese lab leak, albeit with a “low confidence” rating–the lowest on a three-tier scale (low, medium, high)–indicating the evidence remains inconclusive.

What do I do with expired medicine? Don’t use it, for a start…

When last did a headache have you reaching into your medicine cabinet—and finding a bottle of aspirin that expired three years ago? Did you take it anyway? And, if you decided instead to get rid of those out-of-date painkillers, how did you do it? If you chose to throw it in the garbage or flush it down the toilet, you’re far from alone: a 2020 research review found that “disposal of pharmaceuticals by garbage and sewer is still the most common method in many countries with the absence of the proper disposal of expired medications from the patient side.”

Novel bone marrow transplant shows high success in curing sickle cell disease

A bone marrow transplant process co-developed by investigators at the Johns Hopkins Kimmel Cancer Center is safe and curative for adults with sickle cell disease, according to results of a trial completed at Johns Hopkins and about 20 additional cancer centers nationwide and in London. The treatment, available at multiple U.S. medical centers, is a viable and less costly alternative to recently approved gene therapy products for sickle cell disease, the authors say.

Neuroforecasting—using brain scans to forecast human choice at scale

Neuroimaging can capture brain activity in response to stimuli before a person decides how to respond. Initial affective responses—broadly good or bad feelings about a stimulus—have been associated with activity in evolutionarily conserved subcortical and cortical circuits including the nucleus accumbens (NAcc) and anterior (AIns). Activity then continues through integrative circuits associated with more deliberative and reflective processing. Previous work has suggested that the early affective responses may be more broadly shared across individuals than the final choice behavior.