Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer’s disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer’s disease in underrepresented groups. The work is published in the Alzheimer’s & Dementia journal.
Genetic study challenges understanding of cancer predisposition
Despite what was previously thought, new research has shown that genetic changes alone cannot explain why and where tumors grow in those with the genetic condition neurofibromatosis type 1 (NF-1). Understanding more about the factors involved could, in the future, facilitate early cancer detection in NF-1 patients and even point towards new treatments.
Novel cancer treatment uses bacterial toxin to train immune system
Researchers at the University of Texas MD Anderson Cancer Center have developed a novel antibody-toxin conjugate (ATC) designed to stimulate immune-mediated eradication of tumors. According to preclinical results published in Nature Cancer, the new approach combines the benefits of more well-known antibody-drug conjugates (ADCs) with those of immunotherapies.
Ginseng: The dual-purpose herb for health and healing
For more than 2,000 years, Panax ginseng has been a cornerstone of traditional Chinese medicine, renowned for its nourishing and healing properties. In today’s world, challenges such as subfertility and an aging population have intensified the need for natural, holistic remedies.
‘Culturally unsafe’ health care putting Indigenous youth at risk in Australia
Indigenous children and young adults are dying from rheumatic heart disease due to “culturally unsafe” and inaccessible health care in Australia, University of Queensland researchers have found.
The COVID ‘contrarians’ are in power, some believe
In October, Stanford University professor Jay Bhattacharya hosted a conference on the lessons of COVID-19 in order “to do better in the next pandemic.” He invited scholars, journalists, and policy wonks who, like him, have criticized the U.S. management of the crisis as overly draconian.
Morning blue light therapy boosts sleep and activity in seniors
Blue-enriched light can improve sleep quality and daily activity in older adults living at home, according to new research from the University of Surrey. Researchers found that this type of light therapy led to greater daytime activity, earlier bedtimes, regular sleep patterns and improved sleep quality, offering a promising, non-pharmacological approach to address age-related sleep challenges.
Killer T cells could hold key to future ‘bird flu’ vaccines, study suggests
Scientists at La Trobe University have identified a possible defense for humans against the influenza virus H5N1—commonly known as “bird flu”—which could open avenues of research for new vaccine development.
Distressing experiences of death and dying in care homes during COVID-19 pandemic
Research led by Lancaster University has revealed that the exceptional circumstances early in the COVID-19 pandemic led to distressing experiences of death and dying in care homes.
Research highlights wide variation in prostate cancer testing between GP practices
A large-scale study has found huge variation between GP practices on whether they are likely to pick up prostate cancer using a blood test.