CPAP therapy may not improve neurocognition for some people with obstructive sleep apnea

Continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea is most effective in improving neurocognition in people who have a high arousal threshold, according to a new research analysis. The study, published in the European Respiratory Journal, suggests that CPAP, currently used as a one-size-fits-all treatment, may not be beneficial for all people with obstructive sleep apnea.

Early detection and treatment can lessen the impact of heart valve disease

More than 60,000 people die from heart valve disease (HVD) in the U.S. each year, according to the American Heart Association 2025 Heart Disease and Stroke Statistical Update. Additionally, data from the Statistical Update shows that more than 28 million people worldwide are living with some type of heart valve disease, an increase of more than 30% in the past decade.

Machine learning tool decodes immune receptor sequences to diagnose multiple diseases

Stanford University researchers developed a machine learning-based method capable of diagnosing multiple diseases using B cell and T cell receptor sequences. The model, called Machine learning for Immunological Diagnosis (Mal-ID), distinguished between COVID-19, HIV, lupus, type 1 diabetes, influenza vaccination response, and healthy states, achieving near-perfect classification.

Telemedicine’s rise: A potential check on low-value medical testing

Low-value care—medical tests and procedures that provide little to no benefit to patients—contributes to excess medical spending and both direct and cascading harms to patients. A research team from Mass General Brigham and their collaborators have found that telemedicine may help to reduce the use of low-value tests. The work is published in JAMA Internal Medicine.