Islet transplantation with blood vessel cells shows promise to treat type 1 diabetes

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells and reversed diabetes in a preclinical study led by Weill Cornell Medicine investigators. The new approach, which requires further development and testing, could someday enable the much wider use of islet transplants to cure diabetes.

Certain glucose-lowering meds associated with lower risk for COPD exacerbations

For patients with type 2 diabetes (T2D) and chronic obstructive pulmonary disorder (COPD), sodium-glucose cotransporter-2 inhibitors (SGLT-2is) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are associated with a reduced risk for moderate or severe COPD exacerbations compared with dipeptidyl peptidase 4 inhibitors (DPP-4is), according to a study published online Feb. 10 in JAMA Internal Medicine.

HIV stigma tied to moral judgments, complicating destigmatization efforts

Persistence of stigma toward people living with HIV has puzzled scientists looking at the numerous destigmatization campaigns that have taken place in the U.S. in the four decades since its initial discovery. Scientists have explained the presence of stigma with the fact that people with HIV have in the past been legally excluded and marked as criminals, and because of the overlap in LGBTQ+ populations and HIV-positive people.