Preeclampsia, a complication of pregnancy characterized by high blood pressure and high levels of protein in the urine (proteinuria), indicating damage to the kidneys or other organ damage, is the main cause of maternal-fetal death in Brazil and the runner-up worldwide. In a Brazilian study published in the journal PLOS ONE, the pattern of substances present in patient blood samples varied according to the severity of the preeclampsia concerned.
Novel PET tracer reveals potential for recovery in spinal cord injuries
A novel PET technique that visualizes spinal cord injuries provides critical information about which patients may be able to regain mobility, according to new research published in the February issue of The Journal of Nuclear Medicine. By detecting intact nerve connections in the injured spinal cord, a newly developed radiotracer has the potential to help diagnose injuries more precisely, monitor recovery, and evaluate the effectiveness of new therapies in clinical trials.
Plant-rich, low saturated-fat diet associated with reduced psoriasis severity
A diet of fruits and vegetables, whole grains, low-fat dairy foods and lean meats, low in salt and sugar, is associated with reduced psoriasis severity, new research finds.
Researchers identify novel gene behind neurodevelopmental syndrome for enhanced clinical treatment
A clinical research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), and international genetic researchers led a global research study using multi-omics analysis and identified a novel gene, DDX39B, for a rare disease.
New regulations for fair play in roller skiing thanks to Swedish students
The sport of roller skiing has long been plagued with concerns. The wheels of the skis roll differently, which can cause the individual’s speed to vary considerably, and as such, the finish times can be impacted by several minutes.
Stealth virus: How Zika builds tunnels to covertly infect cells of the placenta
Infection with Zika virus in pregnancy can lead to neurological disorders, fetal abnormalities and fetal death. Until now, how the virus manages to cross the placenta, which nurtures the developing fetus and forms a strong barrier against microbes and chemicals that could harm the fetus, has not been clear. Researchers at Baylor College of Medicine with collaborators at Pennsylvania State University report in Nature Communications a strategy Zika virus uses to covertly spread in placental cells, raising little alarm in the immune system.
A ‘twin epidemic’: Co-prescribed stimulants and opioids linked to higher opioid doses
The combination of prescribed central nervous system stimulants, such as drugs that relieve ADHD symptoms, with prescribed opioid medications is associated with a pattern of escalating opioid intake, a new study has found.
Language barriers in health care: Patient-doctor common tongue key to decreasing cardiovascular disease and longer life
A positive patient-doctor relationship is an ingredient to a healthy life, and new research has zeroed in on the impact common language in the relationship can have by decreasing cardiovascular disease for the benefit of a longer life.
Packing lipid nanoparticles with tumor proteins to boost cancer vaccine potency
The concept of using vaccines to treat cancers has been around for several decades. A vaccine was first approved for prostate cancer in 2010, and another was approved in 2015 for melanoma. Since then, many therapeutic—as opposed to preventive—cancer vaccines have been in development, but none are approved. One hurdle is the difficulty in finding antigens in tumors that look foreign enough to trigger an immune response.
How genetics shape blood proteins during development from childhood to adolescence
Blood proteins serve as crucial indicators of health and disease risk throughout development. Now, researchers at the University of Copenhagen and the Max Planck Institute of Biochemistry have revealed how these proteins are regulated during childhood and adolescence, providing a vital foundation for understanding disease mechanisms and developing better diagnostic tools.