Vitamin B3 derivative improves health and complications in rare premature aging disorder in clinical trial

Werner syndrome (WS), a rare genetic disorder that causes accelerated aging. From their twenties, patients develop gray hair, hair loss, cataracts, diabetes, and other age-related conditions normally seen in the elderly. Additionally, patients develop severe and untreatable skin ulcers, often requiring limb amputation, and face early death from cardiovascular diseases or cancer. This debilitating condition, which affects approximately nine per million people in Japan, lacks effective treatment options.

Brain care score strongly correlates with risk of cardiovascular disease and three most common cancers worldwide

A new study from researchers at Mass General Brigham has found that a higher McCance Brain Care Score not only associates with the risk of brain-related conditions such as stroke, dementia, and depression but also strongly associates with developing cardiovascular disease and three common types of cancer. Their results are published in Family Practice.