The AHOMKA platform, an innovative mobile app for patient-to-provider communication that was developed through a collaboration between the School of Engineering and leading medical institutions in Ghana, has yielded positive results in tests with patients at high risk for heart attack or stroke.
Novel method combines heart biopsy and device implantation to reduce risk of complications
Endomyocardial biopsy (EMB) is a valuable method for diagnosing a range of cardiac conditions, but there is a risk of complications due to its invasive nature. Researchers have now found a way to combine right ventricular (RV) septal EMB, exploiting the benefit of 3D curved conduction system pacing (CSP) sheaths, with subsequent cardiac implantable electronic device (CIED, devices like pacemakers or defibrillators to regulate heart rhythm) implantation, using the same sheath.
Muscle-building supplements linked to body image disorder in young adults
Protein shakes and pre-workout mixes are popular among gym-goers, but they might signal a deeper issue for some young adults.
European study highlights inequalities in diagnosis and treatment of biliary tract cancer
Biliary tract cancer is increasing in incidence and mortality across Europe, with more people under the age of 60 years old now impacted by the disease. However, despite this, knowledge about these tumors remains low both among health professionals and authorities, as well as in society in general.
Novel computational tool for identifying synergistic drug combinations developed
Researchers at the Icahn School of Medicine at Mount Sinai have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of combination therapies for complex diseases. The study, published in Briefings in Bioinformatics on February 20, highlights iDOMO’s ability to identify synergistic drug combinations using gene expression data, outperforming existing methods.
Unfolded protein response: A key regulator of intestinal health and disease
The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system. To maintain homeostasis, intestinal epithelial cells (IECs) must efficiently manage protein production and secretion, a process tightly controlled by the unfolded protein response (UPR).
Research links grape consumption to improved muscle health in both men and women
A new study from Western New England University (WNE) has revealed that long-term grape consumption significantly impacts muscle health, with notable benefits for both men and women. The research, published in the journal Foods, suggests that a diet including grapes can modify gene expression in muscle, potentially offering a new nutritional strategy for maintaining muscle mass and function.
Study yields unexpected results from empagliflozin after heart attack
A new study, authored by KBH Professor Jan Inge Henter and published in the New England Journal of Medicine, has investigated whether the drug empagliflozin can reduce the risk of heart failure and death in patients who have recently suffered a heart attack.
User-friendly portal links molecular and clinical data to boost metabolic disease research
Researchers at Karolinska Institutet and Helmholtz Munich, among others, have developed a user-friendly portal with comprehensive data on human adipose tissue. The portal offers researchers and clinicians an opportunity to explore the biology of adipose tissue, right down to the individual cell level, without any requirement for knowledge in bioinformatics. The study is published in the journal Cell Metabolism.
Butterfly wings inspire new imaging technique for cancer diagnosis
Researchers at the University of California San Diego have found an unusual ally in the quest to make cancer diagnosis faster, more accurate and more accessible worldwide: the Morpho butterfly. Known for its shimmering blue wings, the Morpho butterfly owes its brilliance not to pigments but to microscopic structures that manipulate light. Now, researchers are harnessing those same structures to gain detailed insights into the fibrous makeup of cancer biopsy samples—without the need for chemical staining or expensive imaging equipment.