In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent.
Jumbled proteins paint a bold target on the backs of brain tumors
Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue. Now, researchers at UC San Francisco have found that some cancers, like deadly brain cancer (glioma), make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
Text message tool addresses ‘time toxicity’ for cancer patients
Cancer patients spend a lot of time on their care. Meeting with doctors and other members of their health care team, getting labs and other tests, picking up prescriptions, and undergoing treatment all takes time. So does getting to and from each appointment, sitting in the waiting room between each appointment, and so on.
Methadone treatment shown to improve HIV care for formerly incarcerated individuals
When transitioning from prison to the community, formerly incarcerated individuals face numerous challenges, including lack of employment, housing, and health care. This transition is more precarious for those with HIV or opioid use disorder, who—due to these diseases—have an increased risk of medical complications and even death.
Large-scale study reveals rates of drug use among homeless adults and treatment barriers
Less than half of people experiencing homelessness regularly used illicit drugs in the prior six months. The most common drugs used by this population aren’t opioids but methamphetamines. And a significant percentage of people who are homeless and use drugs regularly have tried, but have been unable to receive treatment.
Peaking earlier: Six-second max power test for athletes outperforms standard 30-second version
A six-second cycling test has been shown to reliably and efficiently measure peak power in endurance athletes, offering an appealing alternative to the standard 30-second test.
How medical treatments devised for war can quickly be implemented in US hospitals to save lives
For decades, military doctors faced a critical challenge: What’s the best way to safely and effectively deliver oxygen to patients in remote combat zones, rural hospitals or disaster-stricken areas?
Traumatic brain injuries have toxic effects that last weeks. Antioxidant addresses that damage in mice
Traumatic brain injury is a leading cause of death and disability in the world. Blunt force trauma to the brain, often from a bad fall or traffic accident, accounts for the deaths of over 61,000 Americans each year. Over 80,000 will develop some long-term disability.
Innovative technology enhances cellular and molecular insights into kidney lesions
Researchers have demonstrated the feasibility of a morphological-based approach to interpreting spatial transcriptomic (ST) data, helping to improve understanding of the lesions that occur in chronic kidney disease (CKD), at both the cellular and molecular levels. A recent study in The American Journal of Pathology, details how this new method could lead to the identification of new biomarkers and therapeutic strategies for patients.
Australian women will soon be eligible for a menopause health check—here’s what to expect
The federal government has recently pledged to create a new Medicare rebate for menopause health assessments. It’s due to be available from July 1.