People in their late teens and early 20s may be more sensitive to nicotine and more susceptible to nicotine addiction than middle-aged adults, according to a new study in mice from researchers in the Penn State Department of Biobehavioral Health. The results provide evidence that the effects of drugs on the body—both medication and misused substances—change over the lifespan in ways that clinicians and researchers need to consider when developing and prescribing treatments, the researchers said.
Guidelines needed for interpreting continuous glucose monitoring reports in those without diabetes, say researchers
With the Food and Drug Administration now allowing the over-the-counter purchase of continuous glucose monitors (CGMs)—small sensors that penetrate the skin to measure glucose levels in real time—there is high consumer interest in the use of these devices for health and wellness, even among people without diabetes. However, a new study led by researchers from Boston University Chobanian & Avedisian School of Medicine has found there is no consensus on how clinical experts interpret CGM reports from people without this disease.
NIH research funding drops $1B under Trump administration
Federal funding for medical research has dropped by roughly $1 billion this year, raising alarm among universities, medical centers and lawmakers who warn the shortfall could slow progress in cancer, diabetes and heart disease research.
Guidance provided for primary care providers to identify biliary atresia in newborns by 2 to 4 weeks
In a clinical report issued by the American Academy of Pediatrics and published online Feb. 18 in Pediatrics, recommendations are presented to assist primary care providers in identifying biliary atresia in newborns by 2 to 4 weeks of life.
From 2019 to 2020, ophthalmic procedures in seniors decreased by 17.9%
There was a notable decrease in common ophthalmic procedures among Medicare beneficiaries during the first year of the COVID-19 pandemic, according to a study published Feb. 6 in JAMA Ophthalmology.
Treating liver fibrosis and metabolic dysfunction-associated steatohepatitis: Research identifies novel mechanism
Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis and hepatocellular carcinoma. While fibroblast growth factor 21 (FGF21) analogs have shown promise in clinical trials, their underlying molecular mechanisms remain unclear.
Paying attention to four health factors can help prevent new heart syndrome
About 90% of U.S. adults meet the criteria for a newly recognized syndrome that comes from a combination of heart disease, kidney disease, type 2 diabetes and obesity. This cluster of chronic health conditions is called cardiovascular-kidney-metabolic (CKM) syndrome. It can be prevented by paying attention to four health factors, according to scientific experts at the American Heart Association, a global force changing the future of health for all.
Five things to know about fainting: The heart’s role and when it may signal serious condition
You may have heard that people who feel faint should sit with their heads between their knees, but is that true? And how can you tell whether you or someone else who has fainted should go to the emergency department or perhaps even see a cardiologist? Elijah Behr, M.D., a cardiologist at Mayo Clinic Healthcare in London, explains five things it is important to know about fainting.
Multiple sclerosis: Cell-catching implant helps identify successful treatment in mice
A sponge-like implant in mice has helped guide a treatment that slowed or stopped a degenerative condition similar to multiple sclerosis in humans. It has also given University of Michigan researchers a first look at how primary progressive multiple sclerosis, the fastest-progressing version of the disease, attacks the central nervous system early on.
Mouse model uncovers how lung cells manage severe asthma inflammation
A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for asthma, including biologic therapies. This is especially true for a subtype known as eosinophilic asthma—asthma that’s related to the recruitment and overactivation of white blood cells in the lungs called eosinophils.