Vision changes are an inevitable part of aging, but why are some more susceptible to age-related eye diseases and why do some individuals experience more severe decline than others? New research from The Jackson Laboratory (JAX) reveals that genetics play a key role in how the eye ages, with different genetic backgrounds influencing retinal aging in distinct ways.
FDA approves more broadly protective meningococcal vaccine
The U.S. Food and Drug Administration has approved Penmenvy (Meningococcal Groups A, B, C, W, and Y Vaccine) for active immunization against invasive meningococcal disease (IMD), according to a press release from GlaxoSmithKline (GSK).
Executive order blocks federal funds for schools that require COVID vaccines
President Donald Trump signed an executive order withholding funding from schools and universities that require students to be vaccinated against COVID.
Sex differences in heart cells may influence disease outcomes
Heart disease is the number one killer of men and women, but it often presents differently depending on sex. There are sex differences in the incidence, outcomes, and age of onset of different types of heart problems. Some of these differences can be explained by social factors—for example, women experience less-well recognized symptoms when having heart attacks, and so may take longer to be diagnosed and treated—but others are likely influenced by underlying differences in biology.
Counter-Strike players faster at decision-making, study shows
One of the world’s most popular first-person shooter games—Counter-Strike—could help to improve people’s cognitive abilities, according to research from the University of Sheffield.
Rare genetic syndrome affects male and female brains in distinct ways
Researchers at Tel Aviv University, led by Prof. Illana Gozes, examined the effects of different mutations in the ADNP protein, which is essential for normal brain development and aging, on the brain cells of mice—distinguishing between males and females.
Machine learning sheds light on how the human brain perceives feeling
How the brain feels about the world around it is the subject of a new paper published in Proceedings of the National Academy of Sciences, co-authored by Edward A. Vessel, the Eugene Surowitz Assistant Professor of Computational Cognitive Neuroscience of the City University of New York Colin Powell School for Civic and Global Leadership.
Neurons linked to empathy: Study reveals brain cells that help us understand others
Researchers at Washington University in St. Louis Medicine Mallinckrodt Institute of Radiology have identified specific neuronal cells that are essential to our understanding of other people. Runnan Cao, Ph.D., an instructor in radiology and former postdoctoral fellow in the lab of Shuo Wang, Ph.D., an associate professor of radiology, identified more than 700 such neurons in the human brain. These cells are involved in “social inference,” our ability to read cues from other people’s body language and expressions to draw conclusions about what they are feeling or thinking.
Novel antibiotic BTZ-043 can also target TB bacteria hiding in dead lung tissue
Every year, 10 million people contract tuberculosis (TB), a disease caused by the bacterium Mycobacterium tuberculosis (Mtb), and approximately 1.5 million patients succumb to the disease. Treatment of TB usually requires several months of antibiotic therapy, but the rise of drug-resistant forms of TB has led to an urgent need for new drugs.
SMYD3 enzyme found to suppress antiviral immune response
Interferon regulatory factor 3 (IRF3) is a key transcription factor in the type I interferon signaling. Its activation must be tightly controlled to efficiently activate innate immunity while avoiding its overactivation. However, the precise regulation of IRF3 and the underlying mechanisms remain unclear.