Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell’s nuclear membrane. The findings, by a University of Pittsburgh team using the Bridges-2 system at the Pittsburgh Supercomputing Center, suggest how the capsid may deform to fit through the nuclear pores, revealing a potential target for future AIDS therapies.
Leisure-time physical activity is key for type 2 diabetes risk reduction, research shows
Researchers have found that engaging in moderate to vigorous physical activity during leisure time, regardless of occupational physical activity, is associated with a reduced risk of type 2 diabetes. A combination of sedentary leisure-time activity and demanding occupational activity may increase the risk.
Abortion bans in the US linked to increased births and infant mortality, studies find
Johns Hopkins Bloomberg School of Public Health researchers analyzed the effects of abortion bans in the U.S., identifying increases in both birth rates and infant mortality in states that implemented complete or six-week abortion bans.
Racial disparities seen in care after abnormal mammograms
Despite similar availability of diagnostic technologies to women of different racial and ethnic groups, significant disparities were seen in who actually received same-day diagnostic services and biopsies after abnormal mammogram findings, new research shows.
AI model automatically segments MRI images, reducing radiologist workload
Research scientists in Switzerland have developed and tested a robust AI model that automatically segments major anatomic structures in MRI images, independent of sequence, according to a study published in Radiology. In the study, the model outperformed other publicly available tools.
Study sheds light on how people’s DNA affects their response to smoking cessation drug
The effectiveness of a common drug to quit smoking could be down to people’s genes, according to a study from the University of Leicester (United Kingdom).
Using CRISPR to remove extra chromosomes in Down syndrome
Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro proof-of-concept study.
Taking a break from smartphones: Study confirms its benefits
A month-long randomized control trial confirms that reducing the time spent on smartphones to access the internet makes people happier and more focused.
Feel like you’re in a funk? What you can do to get out of it and prevent it from happening in the future
Are you feeling worn out? Struggling with lingering sadness, anxiety or feelings of indifference? If so, you might be stuck in a funk.
Researchers look for the best ways to help people with HIV quit smoking
Human immunodeficiency virus (HIV) treatment has gotten so good that people can take a pill once a day to achieve viral suppression that lets them live much longer than anyone could have imagined just a few decades ago.