Next-gen Alzheimer’s drugs extend independent living by months

In the past two years, the Food and Drug Administration has approved two novel Alzheimer’s therapies, based on data from clinical trials showing that both drugs slowed the progression of the disease. But while the approvals of lecanemab and donanemab, both antibody therapies that clear plaque-causing amyloid proteins from the brain, were greeted with enthusiasm by some Alzheimer’s researchers, the response of patients has been muted.

Brain rhythms can predict seizure risk in Alzheimer’s disease patients, study finds

A UCLA Health research team has identified changes in brain rhythms that indicate seizure activity in Alzheimer’s patients. The findings, published in Brain Communications, build on UCLA neurologist and senior author Dr. Keith Vossel’s pioneering work that first linked silent epileptic activity to cognitive decline in Alzheimer’s disease.

This is what happens to the body when HIV drugs are stopped for millions of people

A generation has passed since the world saw the peak in AIDS-related deaths. Those deaths—agonizing, from diseases the body might otherwise fight off—sent loved ones into the streets, pressuring governments to act. The United States eventually did, creating PEPFAR, arguably the most successful foreign aid program in history. HIV, which causes AIDS, is now manageable, though there is still no cure.