In the past two years, the Food and Drug Administration has approved two novel Alzheimer’s therapies, based on data from clinical trials showing that both drugs slowed the progression of the disease. But while the approvals of lecanemab and donanemab, both antibody therapies that clear plaque-causing amyloid proteins from the brain, were greeted with enthusiasm by some Alzheimer’s researchers, the response of patients has been muted.
Innovative molecular therapies target and disrupt uncontrollable growth of cancer cells
Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the uncontrollable growth of cancers at their roots.
A step towards aphasia treatment: Study maps new brain regions behind intended speech
Imagine seeing a furry, four-legged animal that meows. Mentally, you know what it is, but the word “cat” is stuck on the tip of your tongue.
Senators call on FDA to act against misleading weight-loss drug commercials
Commercials run by the telehealth company Hims & Hers have been placed under the microscope as lawmakers are calling out the advertisement of prescriptions for injectable weight-loss drugs without disclosing safety and risk information.
Enjoying Valentine’s Day when a loved one has Alzheimer’s
Love doesn’t fade when one member of a family develops Alzheimer’s disease, but times of intimacy like Valentine’s Day can become tougher.
Blood transfusions at the scene save lives, but ambulances are rarely equipped to do them
More than 60,000 people in the U.S. bleed to death every year from traumatic events like car crashes or gunshot wounds, or other emergencies, including those related to pregnancy or gastrointestinal hemorrhaging. It’s a leading cause of preventable death after a traumatic event.
Brain rhythms can predict seizure risk in Alzheimer’s disease patients, study finds
A UCLA Health research team has identified changes in brain rhythms that indicate seizure activity in Alzheimer’s patients. The findings, published in Brain Communications, build on UCLA neurologist and senior author Dr. Keith Vossel’s pioneering work that first linked silent epileptic activity to cognitive decline in Alzheimer’s disease.
Consumer devices show promise for reliable remote cognitive speech assessments
A new study led by Prof. Li Hai’s team from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has evaluated the reliability of speech acoustic features across common consumer-grade mobile devices.
This is what happens to the body when HIV drugs are stopped for millions of people
A generation has passed since the world saw the peak in AIDS-related deaths. Those deaths—agonizing, from diseases the body might otherwise fight off—sent loved ones into the streets, pressuring governments to act. The United States eventually did, creating PEPFAR, arguably the most successful foreign aid program in history. HIV, which causes AIDS, is now manageable, though there is still no cure.
Guardian molecule keeps cells on track: New perspectives for the treatment of liver cancer
A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the German Cancer Research Center (DKFZ), the Hector Institute für Translational Brain Research (HITBR), and from the European Molecular Biology Laboratory (EMBL).