Two new PET radiotracers have outperformed the only current Food and Drug Administration (FDA) approved radiotracer for detecting tau tangles in the brain, a hallmark of Alzheimer’s disease. In a head-to-head comparison of the three imaging agents, the next-generation radiotracers exhibited higher binding to Alzheimer’s disease brain tissue and a greater selectivity for identifying the tangles. This research, which was published in the January issue of The Journal of Nuclear Medicine, could play a key role in measuring outcomes of clinical trials for Alzheimer’s disease treatments.
Rheumatoid arthritis causally linked to prostate cancer
Genetically predicted rheumatoid arthritis (RA) is causally associated with prostate cancer (PCa), according to a study published online Jan. 10 in Medicine.
In HER2+ colorectal cancer, anti-HER2 therapy may be less toxic alternative
Patients whose metastatic colorectal cancer has progressed following chemotherapy and who lack mutations in the RAS and BRAF genes (RAS/BRAF wild-type) are typically treated with EGFR inhibitors. For those whose tumors also demonstrate HER2 amplification (extra copies of the HER2 gene), this therapy may be less effective.
CBD reduces alcohol cravings in people suffering from alcoholism, clinical trial finds
A new study shows that cannabidiol (CBD) can reduce the craving for alcohol in people suffering from alcoholism. CBD is a natural component of the cannabis plant and has no intoxicating effects.
FDA OK’s Ozempic to protect kidneys in type 2 diabetes patients
A popular diabetes drug just got a major new approval—and it could be a game-changer for millions of Americans at risk for kidney failure.
Navigating nutrition during cancer treatment: A dietitian’s advice
During cancer treatment, our bodies require optimal nourishment, so eating well is especially important.
New tool tracks diseases from wastewater in EU
The European Commission has just launched a new tool that supports the tracking of the spread of infectious diseases by analyzing wastewater: the European Wastewater Surveillance Dashboard. It displays data from across the EU by bringing together existing national and research-based dashboards. By providing near real-time information on pathogen trends, the dashboard can support public health authorities in their efforts to track, predict, and respond promptly to disease outbreaks.
Diagnostic stewardship optimizes detection of pediatric appendicitis
Abdominal pain is among the most common reasons children are taken to the emergency department. A small proportion of them usually have appendicitis, and timely detection is essential.
Stress during pregnancy could leave traces in placenta that affect baby’s development, study suggests
Maternal stress could leave epigenetic imprints on genes in the placenta associated with cortisol—a necessary hormone for fetal development—and this would affect the baby’s development from very early stages, according to a paper published in the journal European Neuropsychopharmacology.
Changing cholesterol over time tied to risk of dementia
Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a study published in the January 29, 2025, online issue of Neurology.