All posts by : Felistas

Major uncertainties remain about the impact of puberty blockers and gender-affirming hormone therapy on children and young people with gender-related distress (gender dysphoria), making it impossible to determine conclusively whether they help or harm, finds two pooled data analyses of the available evidence, published online in the Archives of Disease in Childhood.

Pulmonary fibrosis is a rare, chronic disease that causes scarring in the lungs, making breathing difficult for people who suffer with it. And, as University of South Florida pulmonologist Dr. Jose Herazo-Maya knows all too well, it is generally irreversible.

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated with poor survival rates and a markedly reduced quality of life.

Researchers from The University of Queensland are shining a light on the link between greenspace exposure and better health in the hope of influencing future urban greening policies.

An active commute that involves exercise can reduce the number of sick days and lower the risk of long sickness absences. Commuting by bicycle in particular is associated with a lower risk of sickness absence. The message to employers is clear: It pays off to promote forms of commuting that involve exercise.

A recent study conducted by the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) found that mislabeled NSAID (Non-Steroidal Anti-Inflammatory Drug) allergies for stroke patients hinders the use of effective medications for them, leading to poorer treatment outcomes. It also revealed that when stroke survivors with NSAID allergy labels underwent testing, 80% were found to be mislabeled.

A case report published in Eurosurveillance on an adult with an imported case of leprosy in Ireland shows that there are notable challenges in tackling the disease in settings where it is rare.

To remain mentally fit for as long as possible in old age, it is important to understand which risk factors could impact cognitive functioning already early in life. Scientists led by the German Centre for Neurodegenerative Diseases (DZNE) in Greifswald and the Institute of Social Medicine, Occupational Medicine and Public Health (ISAP) at Leipzig University have used data from the German National Cohort (NAKO) to investigate the relationship between aspects of socioeconomic inequality and cognitive functioning. The work is published in the journal Aging, Neuropsychology, and Cognition.

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in Genome Research.

Neuroblastoma is the most common extracranial solid tumor in children, with nearly 50% of cases diagnosed at an advanced stage, often with metastatic disease. Despite advances in treatment, survival rates for high-risk and relapsed/refractory neuroblastoma remain dismal, and options like autologous stem cell transplantation and immunotherapy are frequently unavailable in low- and middle-income countries.