Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include osteoporosis, sexual dysfunction and blood clots.
Using machine learning to predict how people diagnosed with major depressive disorder respond to treatment
Major depressive disorder (MDD) is a debilitating mental health condition characterized by persistent low mood, loss of interest in everyday activities, appetite changes, sleep disturbances and, in extreme cases, suicidal thoughts. Millions of individuals worldwide have experienced a depressive episode throughout the course of their lives and reached out to psychiatrists seeking treatment.
BioChatter: Making large language models accessible for biomedical research
Large language models (LLMs) have transformed how many of us work, from supporting content creation and coding to improving search engines. However, the lack of transparency, reproducibility, and customization of LLMs remains a challenge that restricts their widespread use in biomedical research.
Childhood poverty and/or parental mental illness may double teens’ risk of violence and police contact
Living with persistent poverty and/or parental mental illness throughout childhood may double the risk of carrying and/or using a weapon and getting on the wrong side of the law by the age of 17, suggests research published online in the Journal of Epidemiology & Community Health.
Fizzy water might aid weight loss by providing a small boost to glucose uptake and metabolism
Fizzy water might aid weight loss by boosting blood glucose uptake and metabolism—the rate at which the body uses and converts energy—but the effects are so small, drinking it can’t be relied on alone to shed the pounds, concludes a brief analysis published in the open access journal BMJ Nutrition Prevention & Health.
Muscular strength and good physical fitness linked to lower risk of death in people with cancer
Muscular strength and good physical fitness are linked to a significantly lower risk of death from any cause in people with cancer, finds a pooled data analysis of the available evidence, published online in the British Journal of Sports Medicine.
Research elucidates the mechanism behind frontotemporal lobar degeneration
Researchers have uncovered the mechanism underlying frontotemporal lobar degeneration (FTLD) caused by variants in the valosin-containing protein (VCP) gene. Their study, which used a fruit fly model, reveals key insights into the disease, laying the groundwork for future therapeutic development.
Biosensing platform simultaneously detects vitamin C and SARS-CoV-2
In the COVID-19 pandemic era, at-home, portable tests were crucial for knowing when to wear a mask or isolate at home. Now, Penn State engineering researchers have developed a portable and wireless device to simultaneously detect SARS-CoV-2, the virus that causes COVID-19, and vitamin C, a critical nutrient that helps bolster infection resistance, by integrating commercial transistors with printed laser-induced graphene.
Long-range connections between brain regions are scarce, but essential to speed up information transmission
The human brain is formed by a complex network of neural connections and most of them link neighboring brain regions, which are also the most studied to date. But a recent neuroscientific study by Pompeu Fabra University (UPF) and the University of Oxford, published in Proceedings of the National Academy of Sciences, has revealed that connections between distant brain regions, though rarer and less frequent, play a fundamental role in explaining brain dynamics.
Weight-loss treatment for children with obesity has lasting effects, finds study
When children with obesity undergo weight-loss treatment, the results have effects later in life, and the risk of serious health problems and premature death is lower as they reach young adulthood. However, this is not the case for depression and anxiety, reports a study from researchers at Karolinska Institutet published in JAMA Pediatrics.