While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues. Maintaining a balanced diet typically provides sufficient manganese for most individuals; however, high levels of exposure can be toxic, particularly to the central nervous system.
Longitudinal study reveals HPV infection kinetics
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a study published January 21 in the open-access journal PLOS Biology by Samuel Alizon of the National Center for Scientific Research (CNRS), France, and colleagues.
Reversal of lipoprotein alterations in patients with ischemic stroke offers avenues for cardiovascular disease research
A study published by researchers from the Sant Pau Research Institute (IR Sant Pau) and the Stroke Unit of Sant Pau Hospital in the Journal of Lipid Research provides new evidence on the essential role of the qualitative properties of lipoproteins, such as LDL and HDL, in the pathophysiology of cardiovascular diseases, including ischemic stroke.
Q&A: Aging and Alzheimer’s disease—investigating drug effects
The geroscience hypothesis focuses on extending the healthy lifespan by targeting aging mechanisms. Recent advances in biomarkers for biological aging give rise to tools for measuring aging and assessing treatments. Alzheimer’s disease, a major health issue, may benefit from common drugs and early interventions.
Exploring the effectiveness of health behavior interventions and their components for healthy adults
Physical inactivity (insufficient physical activity levels) is a serious public health issue that results in all-cause mortality, cardiovascular disease, diabetes, and obesity. Increasing physical activity among the working-age population, which represents ~65% of the total population, is expected to improve health and prevent disease earlier. Numerous intervention studies have been conducted to increase physical activity levels.
Researcher develops new device for diagnosing erectile dysfunction
Erection problems can have a huge impact on quality of life and health, but current diagnostic methods are painful, uncomfortable and technologically outdated. Ph.D. candidate Evelien Trip has developed a new device that can measure erections more comfortably and painlessly.
New effective treatment for deadly pancreatic cancer may be on its way
Pancreatic cancer is one of the deadliest of all cancers. Only 12% of men diagnosed with pancreatic cancer are alive five years after diagnosis; for women it is 14%.
Gene expression analyses reveal molecular insights into bone remodeling
Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling—a highly regulated process of bone formation and bone resorption (dissolving old and damaged bones), driven by osteoblast and osteoclast bone cells, respectively.
Exercise-activated PanK4 could aid in treating metabolic disorders
Physical activity is not only important for fitness but also for overall health. This is confirmed by a new study, which identified PanK4 as a key regulator of energy metabolism in skeletal muscle, regulating glucose uptake and fatty acid oxidation and being activated by physical exercise.
Studies show AI therapists can provide bias-free counseling that is well received by patients
Two studies by Cedars-Sinai investigators show that artificial intelligence (AI) can be an effective tool for mental health therapy. One study found that therapy sessions with avatars programmed to simulate human therapists earned positive feedback from patients struggling with alcohol addiction.