Researchers at University of California San Diego School of Medicine have published results that shed new light on an old question: what causes aging at the molecular level? Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications. The latter, also known as the epigenetic clock theory, has been widely used by scientists as a consistent, quantitative measure of biological aging.
Scientists identify neurons in mice that induce hibernation-like state
A team led by researchers at Georgia State University has identified a novel group of neurons controlling the brain-heart-gut axis which can be activated to induce a hypometabolic state that resembles hibernation. The discovery could have wide-ranging impacts for scientific fields, ranging from obesity to cardiometabolic health, and even space travel.
Why is obesity linked to irregular heart rhythms? Researchers found one potential mechanism
Atrial fibrillation, or A-fib, is an irregular heart rhythm that increases a person’s risk of stroke, heart failure and even premature death.
Microglia show sex-specific responses, with potentially broad implications in neurological disease research
A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another “crew” of responders is busy clearing debris and repairing injured tissue.
What’s behind preterm birth? Scientists discover a molecular timer
A typical human pregnancy lasts 40 weeks, but most parents know this number is only a rough estimate. Babies are born on a seemingly unpredictable timeline, with a normal pregnancy ranging from 38 to 42 weeks. And 10% of all births are preterm, meaning they occur before 37 weeks of gestation, which puts babies at risk of a host of complications.
Shorter, smarter, safer: Short-course antibiotics prove effective against ventilator-associated pneumonia
Antibiotic overuse is a key driver in the rise of antimicrobial resistance (AMR), a major global health crisis. Researchers from the Yong Loo Lin School of Medicine, NUS (NUS Medicine) and Duke-NUS Medical School have provided compelling evidence that short-course antibiotic treatments can be a game-changer in tackling ventilator-associated pneumonia (VAP), a serious infection common in critically ill patients.
Do two puffs equal a bong hit? Standardized cannabis dosing research aims to find out
UBC Okanagan researchers Drs. Zach Walsh and Michelle St. Pierre have created an Index of Cannabis Equivalence (ICE), a unique approach to standardized cannabis dosing across different consumption methods.
Boosts, not nudges: Behavioral policy approach can foster agency, self-control and ability to make informed decisions
In the face of growing global challenges such as climate change, pandemics, and threats to democratic values, traditional behavioral policy approaches are increasingly coming into question. The once-dominant nudging approach, which seeks to “nudge” people toward better decisions, has been criticized for, among other things, not sufficiently promoting individual autonomy.
New data demonstrate clinical validation of novel prostate cancer test
OncoAssure Ltd, an Irish medical diagnostic company, announced the publication of new data in the journal BJUI Compass that demonstrate the clinical validation of OncoAssure Prostate, a novel biopsy test that provides improved estimation of a patient’s risk of prostate cancer recurrence and allows for optimal treatment selection.
Music supports babies in neonatal intensive care units, neuroimaging study finds
Certain melodies promote brain development in premature infants. For several years, a team of scientists have observed this phenomenon. They now know more precisely which areas of the brain react over time.