Researchers at Baylor College of Medicine and collaborating institutions have improved our understanding of how rotavirus, the most common cause of acute gastroenteritis in children, makes people sick. The study published in Science Advances is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells. These disruptions in calcium signaling affect rotavirus disease severity, providing new insights into how NSP4’s function influences rotavirus virulence. The findings suggest that manipulating NSP4 could lead to new strategies to prevent or treat rotavirus infections.
Mapping the mind: New framework links brainwaves to individual cognitive states
The complexity of the human brain—86 billion neurons strong with more than 100 trillion connections—enables abstract thinking, language acquisition, advanced reasoning and problem-solving, and the capacity for creativity and social interaction. Understanding how differences in brain signaling and dynamics produce unique cognition and behavior in individuals has long been a goal of neuroscience research, yet many phenomena remain unexplained.
Prayer warrior arrested in the George Kalaba murder case, police say
IT has come to light that a wife, who retained her deceased husband’s remains in their residence for two years, was performing rituals with another woman, believing he would be resurrected. Police have since arrested Preteria Mbandama Musela, aged 44, of Luangwa-Garden Compound, in connection with the murder of Mr George Kalaba. This brings the […]
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Prayer warrior arrested in the George Kalaba murder case, police say
IT has come to light that a wife, who retained her deceased husband’s remains in their residence for two years, was performing rituals with another woman, believing he would be resurrected. Police have since arrested Preteria Mbandama Musela, aged 44, of Luangwa-Garden Compound, in connection with the murder of Mr George Kalaba. This brings the […]
The post Prayer warrior arrested in the George Kalaba murder case, police say first appeared on Mwebantu.
Two men die of suffocation in a bus while using a brazier, police say
TWO men from Chingola have died due to suffocation inside a bus where they had slept with a lit brazier.. The victims, Joseph Kakoma 27 and Jackson Kasongo 26, believed to be illegal miners, had gone to a friend’s house after work. Exhausted from the day’s activities, they decided to sleep in a parked Toyota […]
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Don’t give ‘Bulldozer’ bail, ACC tells High Court
THE Anti-Corruption Commission(ACC) has opposed a renewed bail pending appeal application filed by jailed former Lusaka Province Minister Bowman Lusambo,alias, Bulldozer. The commission has urged the Economic and Financial Crimes Court (EFCC) not to release on bail the former Kabushi lawmaker who is serving a four-year jail term because his application for bail lacks merit. […]
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Man in court for trying to have sex with own mum
A taboo is in the face of a 44-year-old woman of Mtendere Township, Lusaka, after her own 22-year-old son walked into her bedroom naked and allegedly attempted to have sex with her. The suspect, Fanizani Phiri, who works at some Tobbaco farm, has since been arrested and charged with attempted incest. Allegations are that on […]
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Unique characteristics of a rare liver cancer identified as clinical trial of new treatment begins
Like many rare diseases, fibrolamellar hepatocellular carcinoma (FLC) mounts a ferocious attack against an unlucky few—in this case, children, adolescents, and young adults. Because its symptoms can vary from person to person, it’s often missed or misdiagnosed until it has metastasized and becomes lethal. Moreover, drug therapies for common liver cancers are not just useless for FLC patients but actually harmful.
New study shows stem cell therapy ‘jump-start’ brain repair after stroke
Every 40 seconds, someone in the United States has a stroke. For survivors of the most common type of stroke, called an ischemic stroke, only about 5 percent fully recover. Most others suffer from long-term problems, including weakness, chronic pain, or epilepsy.
Specific neurons with an immune ‘doorbell’ may influence mood and memory
Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high levels of IL-1 in the brain are linked to neuroinflammation, which can disrupt the body’s stress response, cause sickness-like behaviors, worsen inflammation by activating brain immune cells, and allow immune cells from the body to enter the brain. It also can lead to brain damage by causing support cells to produce harmful molecules. Elevated IL-1 levels are associated with mood disorders, such as depression, and problems with memory and thinking.