Researchers from Singapore’s National Healthcare Group (NHG)’s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune system and resistance to antipsychotic medications in schizophrenia, using changes in immune cell populations to predict potential treatment resistance and initiate the most appropriate treatment sooner.
Change in induction procedures linked to sharp drop in infant mortality after 41 weeks of pregnancy
The proportion of babies dying before and during labor after 41 weeks of gestation has fallen by 47% in Sweden in a relatively short time. This is the result of a major national study. The reduction has occurred since the procedures around induction have changed.
Decoding HIV’s tactics: RNA structures provide new insights into how virus hijacks cells
A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible for AIDS, skillfully hijacks cellular machinery for its own survival.
US announces new funds for mRNA vaccines, fast tracks bird flu tests
President Joe Biden’s outgoing administration on Thursday announced $211 million in new funding to develop mRNA vaccines against emerging biothreats and said it was accelerating bird flu testing, as fears of another pandemic loom.
Discovery could eliminate need to refrigerate vaccines and protein-based drugs
A new storage technique can keep protein-based drugs and vaccines stable without keeping them cold. The discovery, led by researchers at Penn State, could eliminate the need for refrigeration for hundreds of life-saving medicines like insulin, monoclonal antibodies and viral vaccines.
Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made “exciting,” patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors. This emerging technology holds promise for very safe and more effective treatment of cancers with high mortality rates, including liver, ovarian and metastatic breast cancer.
Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made “exciting,” patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors. This emerging technology holds promise for very safe and more effective treatment of cancers with high mortality rates, including liver, ovarian and metastatic breast cancer.
Tagging gene-regulating DNA sequences with barcodes provides insights into human genome
An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. The research is published in the journal Nature.
Tagging gene-regulating DNA sequences with barcodes provides insights into human genome
An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. The research is published in the journal Nature.
TLE6 identified as a protein associated with infertility in male mice
Genetic changes are a significant cause of infertility, impacting over 15% of the global population. TLE6, a major protein involved in early embryonic development, is known to affect female fertility. In a recent study, researchers unraveled its role in male fertility using a novel Tle6-deficient mouse model. Abnormal sperm morphology with a marked reduction in sperm count and motility highlighted the role of Tle6 in sperm function and production, and its potential association with male infertility.