Patients undergoing a donor stem-cell transplant for leukemia or other blood-related cancer require months of specialized follow-up care, traditionally delivered at the center where they received their transplant—often a serious challenge for those who live far away. A large clinical trial by Dana-Farber Cancer Institute investigators shows that patients can fare just as well when they receive some of this care at a local hematology/oncology clinic.
Targeted centrosome inheritance during CD8⁺ T cell division plays role in memory precursor cell generation: Study
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8+ T cell division for the generation of memory precursor cells.
Alcohol raises colorectal cancer risk while calcium protects, study finds
Researchers from the Cancer Epidemiology Unit at the University of Oxford, along with collaborators from international institutions, found significant associations between diet and colorectal cancer risk. Examining data from 542,778 women in the United Kingdom, the study identified a positive correlation between alcohol consumption and colorectal cancer and a protective role for calcium and dairy-related foods.
Strategies to mitigate xylazine-involved fentanyl overdoses: Lessons from Tijuana, Mexico
A recent study published in the Harm Reduction Journal documents the arrival of xylazine to the San Diego-Tijuana border region, and shows the efforts of local physicians to address this emerging challenge in the nation’s overdose crisis.
An expert on happiness uncovers a worrying trend: ‘A collapse in the well-being of young people’
Economist David Blanchflower studies happiness. And for more than two decades, the Bruce V. Rauner 1978 Professor has published over 30 papers revealing a stable pattern for how most people experience happiness and well-being over the course of a lifetime.
UV light–based cell therapy offers new hope for lung transplant patients, reducing rejection and infection risks
Researchers from the Vienna Lung Transplant Program of MedUni Vienna and University Hospital Vienna have published the first prospective, randomized and controlled study on the use of extracorporeal photopheresis (ECP) in lung transplantation in the European Respiratory Journal. The findings could significantly change the standard procedure for rejection reactions after lung transplants.
Early-life infection burden linked to risk for later infections
Early-life infection burden is associated with an increased risk for later moderate-to-severe infections and systemic antibiotic treatments to age 10 or 13 years, according to a study published in JAMA Network Open.
Nonadherence to cancer screening varies by screening type
Nonadherence to cancer screening varies by screening type and sex, according to a study published in JAMA Network Open.
Some combinations of long-term health conditions linked to worse quality of life
Certain combinations of long-term health conditions are associated with worse quality of life and should be taken into account when assessing patients.
Diet, microbes and fat: A new pathway controlling levels of body fat and cholesterol
Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University’s Ithaca campus.