All posts by : Felistas

Russell W. Jenkins, MD, Ph.D., a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is senior author of a new study in Cancer Immunology Research, “TBK1 is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids”.

A multi-institutional team of researchers has created a new and improved genetic map for the laboratory rat, a cornerstone in medical and scientific research. Known as GRCr8, this updated genome assembly enhances the ability to study human diseases, behaviors and genetic traits more precisely.

Holiday weight gain hits home for many come January. These days, folks making resolutions to slim down and get fit have an increasingly popular option to consider: GLP-1s.

The processing of optical information in the retina of the eye, where the light-sensitive photoreceptors and the first nerve cells are located, is one of the most energy-intensive processes in the organism, especially in view of the low relative weight of the retina.

A University of Alberta research team has successfully used machine learning as a tool for earlier detection of attention deficit hyperactivity disorder (ADHD) in kindergarten students.

Researchers at the University of Gothenburg, Sweden, in collaboration with colleagues in China, have discovered an antibody-like molecule that can protect mice from various influenza viruses. The findings could pave the way for new treatments and the development of broader influenza vaccines. The work is published in Nature Communications.

Genetic differences that contribute to how long a person will live and their risk of Alzheimer’s disease have been identified by researchers at UCL and the UK Dementia Research Institute (UK DRI).

People genetically susceptible to Huntington’s disease often see their movement, mood, and cognition decline slowly over time. The cause is related to expansion of repeating DNA units, in which specific strings of genetic code—in this case, a series of cytosine-adenine-guanine nucleotides, or CAG, on one strand of the DNA and cytosine-thymine-guanine, or CTG, on the complementary strand—begin to repeat over and over, expanding to as many as 40 to 120 copies.

Opioid misuse and specifically opioid use disorder (OUD), continues to represent a significant U.S. public health threat, with more than 6 million Americans aged 12 and older meeting the criteria for OUD in 2022. Efforts to ease the crisis have included the development of genetic testing to identify individuals most at risk for OUD.

A Mount Sinai-led team of researchers has enhanced an artificial intelligence (AI)-powered algorithm to analyze video recordings of clinical sleep tests, ultimately improving accurate diagnosis of a common sleep disorder affecting more than 80 million people worldwide.