Electrical stimulation of the spinal cord is a promising strategy for reestablishing walking after spinal cord injury, recent studies show. But for patients suffering from muscle spasms, the stimulation protocols have a limited effect due to the unpredictable behavior of involuntary muscle stiffness related to spasticity. Muscle spasticity affects almost 70% of spinal cord injured patients.
Expert outlines plan to combat antivaccine movement’s next phase
In a recent essay, pediatrician-scientist Peter Hotez proposes a focus on local data, improved benefit-risk communications, actively countering health disinformation, and state-level action to address antivaccine sentiment in the U.S.
Improving cancer risk assessment and patient care: Researchers resolve uncertainty in BRCA2 testing
Findings from a multi-institutional, international study led by researchers from the Mayo Clinic Comprehensive Cancer Center have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer risk.
Deadly bacteria behave differently in Saudi Arabia compared with rest of world, epidemiology study finds
A new multi-institutional study led by King Abdullah University of Science and Technology (KAUST) and the Saudi Ministry of Health (MOH) provides the largest epidemiological analysis in Saudi Arabia of the multidrug-resistant bacteria species Klebsiella pneumoniae, one of the leading causes of nosocomial infections in the world and a global health priority of the World Health Organization. The study finds that the diversity of bacteria in Saudi Arabia differ from other geographical regions, indicating unique health policies are required.
The same gene can drive distinct medulloblastoma types in different ways
A study published in Nature Genetics reveals new insights into how medulloblastoma, the most common malignant brain tumor of childhood, can arise as the cerebellum develops.
AI improves mammography cancer detection rates in large cohort study
An observational, multicenter, real-world study conducted at 12 screening sites in Germany has reported a 17.6% higher cancer detection rate among women aged 50–69 who received AI-supported double-reading mammography screenings compared to those who received standard double-reading. Recall rates remained unchanged.
AI tool uncovers gender disparity in heart disease diagnosis
Women may be missing a diagnosis of a potentially deadly heart condition due to guidelines that don’t account for natural differences in sex and body size, according to a new study led by UCL researchers.
Supported weight management may improve symptoms for people living with long COVID and overweight
Researchers have found that a combination of dietitian and peer-supported weight management may help improve symptoms in people with both long COVID and overweight—however, the study authors stress it was a complex intervention and further research is required.
How a protein affects the ability to secrete insulin in type 2 diabetes
In type 2 diabetes, the body’s ability to release insulin is impaired, which leads to high blood glucose levels. Research led by Lund University shows how the levels of a particular protein are elevated in the pancreas of people with type 2 diabetes. By knocking out the gene for the protein IGFBP7, the researchers discovered that insulin secretion improved.
Using AI to predict the outcome of aggressive skin cancers
Artificial intelligence can determine the course and severity of aggressive skin cancers, such as Merkel cell carcinoma (MCC), to enhance clinical decision making by generating personalized predictions of treatment-specific outcomes for patients and their doctors.