Autoimmune diseases, in which the immune system mistakenly attacks the body’s own healthy cells and tissues, often include a preclinical stage before diagnosis that’s characterized by mild symptoms or certain antibodies in the blood. However, in some people, these symptoms may resolve before culminating in the full disease stage.
Visual cues for dry skin: Psychophysical experiments reveal how skin moisture perception is altered
To clarify the visual cues contributing to skin moisture and dryness, a research team conducted several psychophysical experiments to investigate how image manipulation alters visual perceptions of skin moisture.
Studies find time-release medication keeps adults with ADHD on track, lowers substance use risk
Adults with attention-deficit/hyperactivity disorder (ADHD) who use an extended-release medication are more likely to continue the treatment and have a lower risk of developing substance use disorder, according to two West Virginia University studies.
Cell-based therapy improves outcomes in a pig model of heart attacks
In a large-animal model study, researchers have found that heart attack recovery is aided by the injection of heart muscle cell spheroids derived from human-induced pluripotent stem cells (hiPSCs), that overexpress cyclin D2 and are knocked out for human leukocyte antigen classes I and II.
Global study reveals younger adults face rising gastric cancer risk
A global study reveals a disturbing rise in early-onset gastric cancer, a disease once predominantly affecting older adults but now increasingly impacting younger populations. This shift in disease patterns, uncovered through a 15-year analysis, calls for urgent reevaluation of global health strategies and targeted interventions.
Researchers call for reform in the use of racial data in biomedical research
A recent study published in Synthese challenges the default collection and reliance on ethno-racial data in biomedical research, arguing that these practices often lack scientific or ethical justification. The paper critically examines the widely accepted “fair subject selection” requirement, which mandates proportional representation of racial groups in clinical trials, and suggests that this approach might inadvertently perpetuate scientific inaccuracies and social stereotypes.
High-cost outliers distort public discussions about drug development costs, study says
The typical cost of developing new medications may not be as high as generally believed, with a few ultra-costly medications skewing public discussions about the cost of pharmaceutical research and development, according to a new RAND study.
Study challenges traditional risk factors for brain health in those over 90
A study led by the University of California, Irvine has found cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, not to be associated with an increased risk of such harm in individuals 90 and older.
Bioengineered blood vessels show promise in trauma care
A new type of bioengineered blood vessel has shown strong results in treating severe vascular injuries, potentially offering vascular surgeons a better alternative to synthetic grafts when patients’ veins aren’t suitable for use in repairs.
Immune-targeted approach helps control tuberculosis in mice
Mice infected with the bacteria that cause tuberculosis (TB) fared better when treated with an experimental compound that modulates immune responses than untreated mice did, according to a study led by Christina Stallings, a professor of molecular microbiology at Washington University in St. Louis (WashU) Medicine.