Cart is empty The typical cost of developing new medications may not be as high as generally believed, with a few ultra-costly medications skewing public discussions about the cost of pharmaceutical research and development, according to a new RAND study.
Study challenges traditional risk factors for brain health in those over 90
A study led by the University of California, Irvine has found cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, not to be associated with an increased risk of such harm in individuals 90 and older.
Bioengineered blood vessels show promise in trauma care
A new type of bioengineered blood vessel has shown strong results in treating severe vascular injuries, potentially offering vascular surgeons a better alternative to synthetic grafts when patients’ veins aren’t suitable for use in repairs.
Immune-targeted approach helps control tuberculosis in mice
Mice infected with the bacteria that cause tuberculosis (TB) fared better when treated with an experimental compound that modulates immune responses than untreated mice did, according to a study led by Christina Stallings, a professor of molecular microbiology at Washington University in St. Louis (WashU) Medicine.
Improving outpatient care following non-hospitalized traumatic brain injury
A new systematic literature search has identified the highest priority clinical actions aimed at improving post-acute care for non-hospitalized traumatic brain injury (TBI).
Gene therapy could treat chronic hypereosinophilia
A study published in Human Gene Therapy has involved the generation of a human monoclonal antibody (mAb) directed against human eosinophils. The heavy and light chains of that fully human anti-human eosinophil mAb were delivered via an adeno-associated virus (AAV)-based gene therapy to immunodeficient mice, where they suppressed levels of human eosinophils in vivo.
Study reveals how sex and age influence fat in muscles and bones
Researchers at UT Southwestern Medical Center have discovered sex-specific differences in how fat accumulates in muscle and bone, uncovering patterns that could inform new approaches to treating age-related diseases.
Childhood racial segregation in school tied to late-life cognitive outcomes
Childhood exposure to school segregation is associated with worse late-life cognitive outcomes among older Black adults, according to a study published online Jan. 3 in JAMA Network Open.
AI diagnostics can ease health crisis in war-torn Sudan
Sudanese health authorities are turning to AI to strengthen health systems after dozens of doctors were killed in the country’s almost two-year-long civil war, according to a senior official.
One in four Canadian women are unaware of folic acid’s importance during pregnancy
Approximately one in four women in Canada are unaware of the benefits of taking folic acid before and during pregnancy to prevent certain birth defects—a percentage that has not improved in more than a decade.