All posts by : Felistas

Alcohol-fueled cancer deaths nearly doubled in the United States during the past three decades, with cases among men driving this surge, a new study says.

Why do people get fevers when we get sick?

A recent study on the application of metagenomic next-generation sequencing (mNGS) found that mNGS can achieve early detection of pathogens and accelerate the development of targeted anti-infection treatment plans, thereby improving treatment outcomes and patient prognosis.

Subarachnoid hemorrhage, the third most common type of stroke, accounting for 5–10% of all cases, could be drastically reduced worldwide through health and lifestyle changes, according to NZ, Australian and international researchers.

There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern. Charles Kyriakos Vorkas, MD, an infectious diseases physician-scientist at the Renaissance School of Medicine (RSOM) at Stony Brook University, and colleagues identified a novel population of immune cells that could serve as an alternative target for TB vaccines and immune-directed therapy. Their findings are detailed in a paper published in Scientific Reports.

Researchers from the University of Pittsburgh, University of South Carolina and Emory University have published findings in JAMA Health Forum from a recent study on coverage retention and plan switching among Americans who obtain their health insurance through HealthCare.gov.

There were over 1.5 million “missing Americans” in 2022 and 2023, deaths that would have been averted if US mortality rates matched those of peer countries. Excess US deaths have been increasing for decades, with working-age adults disproportionately affected, and this trend continued during and after the pandemic.

Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have identified a previously undocumented, organ-specific toxicity linked to CD19-targeted CAR T-cell therapy in autoimmune disease. The syndrome, termed local immune effector cell-associated toxicity syndrome (LICATS), affected 77% of patients and resolved without lasting complications.

Researchers led by Maike Sander, scientific director of the Max Delbrück Center, have developed a vascularized organoid model of hormone-secreting cells in the pancreas. The advance, published in Developmental Cell, promises to improve diabetes research and cell-based therapies.

The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell organelles that produce energy essential for life activities through oxidative phosphorylation (mitochondrial respiration), and mtDNA encodes a set of genes required for mitochondrial respiration.