What’s really in our food? A global look at food composition databases

In today’s world, we hear a lot about what we should eat: more vegetables, less sugar and salt, and to obtain locally sourced, sustainable, and nutrient-rich food. But there’s a fundamental question most people don’t think about: How do we actually know what is in our food? The answer lies in food composition databases (FCDBs), which are collections of data about the nutritional content of different foods, from macronutrients like protein and fat, to vitamins, minerals and specialized biomolecules like antioxidants and phytochemicals.

Dad’s mental health linked to kid’s well-being

Dads with poor mental health may be impacting the development of their kids, with Australian research linking mental distress in fathers to poorer social-emotional, cognitive, language, and physical development in their kids. The review, which pooled together the results from 84 studies across 48 groups of people, found that these impacts were generally stronger for mental distress after birth than before birth, suggesting that a father’s mental state may exert a more direct influence on the developing child after birth.

Glial replacement therapy slows Huntington’s disease in adult mice

Huntington’s disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan. These findings shift our understanding of Huntington’s pathology and open a potential path to cell-based therapies in adults already showing symptoms.

AI detects hidden heart disease using existing scans stored in patient records

Mass General Brigham researchers have developed a new AI tool in collaboration with the United States Department of Veterans Affairs (VA) to probe through previously collected CT scans and identify individuals with high coronary artery calcium (CAC) levels that place them at a greater risk for cardiovascular events. Their research, published in NEJM AI, showed the tool called AI-CAC had high accuracy and predictive value for future heart attacks and 10-year mortality. Their findings suggest that implementing such a tool widely may help clinicians assess their patients’ cardiovascular risk.

Researchers identify protein that may help improve the treatment of obesity and cardiovascular disease

Obesity, diabetes and cardiovascular diseases are increasingly present in the population. Brown adipose tissue has a protective function against these prevalent diseases, as it burns calories and can produce body heat from fat. But as the body ages, the activity of brown adipose tissue decreases. This inactivation of brown adipose tissue—also typical of obese people—remains poorly studied in the scientific literature.