Cancer cells mimic Sherpa genes to survive low oxygen

Results of a study show convergent genetic adaptation under hypoxia (lack of oxygen) between populations living at high-altitude in the Himalayan region such as Tibetans and Sherpas, and the development of oxygen-starved cancer cells. The study was directed by Rodrigo Toledo, Head of the Vall d’Hebron Institute of Oncology’s (VHIO) Biomarkers and Clonal Dynamics Group and published in the journal Cancer Discovery.

Skin injury may bring on food allergies

There’s a mysterious connection between our skin and our guts, specifically when it comes to food allergies. For reasons scientists don’t fully understand, chronic skin conditions such as eczema are linked to food allergies; while the national prevalence of childhood food allergies is only around 8%, that prevalence rises to 30% in children with eczema. Researchers have discovered that in some cases, eczema can precede food allergies.

Dynamic profiling technique offers personalized approach to lung cancer treatment

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication. The use of inhibitors against this oncogene—one of the most effective strategies against this type of cancer—has benefited many patients. But, is it possible to know if the treatment will be effective in all those affected?