Researchers at the University of Pittsburgh have developed a nasal swab test for kids that diagnoses specific asthma subtype, or endotype. This non-invasive approach could help clinicians prescribe medications more precisely and pave the way for research toward better treatments for lesser-studied asthma types, which have been difficult to diagnose accurately until now.
Blood test can predict how long vaccine immunity will last, study shows
When children receive their second measles-mumps-rubella vaccine, around the time they start kindergarten, they gain protection against all three viruses for all or most of their lives. Yet the effectiveness of an influenza vaccine given in October starts to wane by the following spring.
Open-access resource simplifies cancer subtype classification for researchers
A multi-institutional team of scientists has developed a free, publicly accessible resource to aid in classification of patient tumor samples based on distinct molecular features identified by The Cancer Genome Atlas (TCGA) Network.
Psychedelic drug therapy may address mental health concerns in people with cancer and addiction
One or two doses of psilocybin, a compound found in psychedelic mushrooms, may improve the mental health of cancer patients when accompanied by psychotherapy, a new report suggests. A second new study found that treatment with psilocybin resulted in lasting, positive personality changes in patients with alcohol use disorder.
Zebrafish protein unlocks dormant genes for heart repair
Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement.
AI-based ultrasound evaluation can improve ovarian cancer diagnoses
A new international study led by researchers at Karolinska Institutet in Sweden shows that AI-based models can outperform human experts at identifying ovarian cancer in ultrasound images. The study is published in Nature Medicine.
Abnormal blood vessel growth in the brain may be an early diagnostic sign of cognitive impairment
Gender differences define how the human brain ages, and telltale biomarkers in the blood may be strongly suggestive of cognitive impairment and dementia, according to a comprehensive new study involving more than 500 people.
World’s largest chimeric gene database promises personalized cancer therapies
A new study conducted at the Scojen Institute for Synthetic Biology at Reichman University’s Dina Recanati School of Medicine announces the launch of the ChiTaRS 8.0 database, the world’s largest collection of chimeric genes (gene fusions) found in humans with cancer and other chronic diseases.
Health officials assess the threat of H5N1
Highly pathogenic H5N1 avian influenza A virus (HPAI H5N1) remains a low risk to the general public, and public health experts in the United States believe that available treatments and vaccines, as well as those in development, are sufficient to prevent severe disease. However, the National Institutes of Health (NIH) and its federal partners remain focused on monitoring the virus and evaluating changes, according to leading officials at the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH.
What is cardiac arrest? Why is it so deadly?
Cardiac arrest is when the heart stops abruptly with little or no warning. It is often fatal. According to American Heart Association data, 9 out of every 10 people who experience cardiac arrest outside of a hospital die.