The NHS must treat at least 10% more non-emergency hospital cases a month if it is to successfully start reducing the hefty backlog caused by the pandemic, according to a new analysis.
Uncovering the link to combating muscle atrophy caused by aging and immobility
The loss of muscle mass, or muscle atrophy, is a relatively common condition in today’s aging and increasingly sedentary societies. While the disuse of muscles is the most frequent catalyst for muscle atrophy, there are several other possible causes, including chronic diseases, injury, and exposure to low-gravity environments, such as spaceships. Despite being a prevalent condition, its underlying mechanisms are complex and not entirely understood.
Smartphone app could help prevent falls in older adults
Researchers at Binghamton University, State University of New York’s Motion Analysis Research Laboratory have developed an app to help study and prevent falls in older adults. Their research is published in the journal Sensors.
HOXA9 tracking reveals RBM5 dual function and therapeutic potential for acute myeloid leukemia
The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes. However, HOXA9 is a difficult protein to target therapeutically, so researchers at St. Jude Children’s Research Hospital looked for ways to extinguish it indirectly.
Pay-for-performance programs may only exacerbate pre-existing disparities, analysis finds
Racial and ethnic minorities in the United States experience higher rates of chronic disease and premature death compared to their white counterparts. For example, Black individuals in the U.S. experience worse health outcomes for acute medical conditions, in part because the care of Black adults is highly concentrated at a limited set of U.S. hospitals, which tend to be under-resourced and operate on thin financial margins.
Persistent fluorinated chemicals tied to higher risk for inflammatory bowel disease
Perfluoroalkyl and polyfluoroalkyl substance (PFAS) exposure is associated with later occurrence of inflammatory bowel disease (IBD), according to a research letter published online Dec. 26 in Clinical Gastroenterology and Hepatology.
Stress, via inflammation, is linked to metabolic syndrome
Lifestyle and genetics, and a range of other factors within and outside our control, are known to contribute to development of metabolic syndrome, a cluster of conditions that add up to increased risk for serious health problems.
Mental illness in patients with chronic kidney disease
Chronic kidney disease (CKD) affects more than 10% of adults worldwide. Mental health is an important yet under-recognized issue in patients with CKD. Depression is common and related to poor prognosis in CKD patients, but previous research has primarily focused on dialysis patients, leading to an insufficient understanding of depression in earlier stages of CKD.
Nutritional acquired immunodeficiency (N-AIDS) found to be the leading driver of the TB pandemic
Tuberculosis (TB) is the leading infectious killer worldwide, with 10.6 million cases and 1.6 million deaths in 2021 alone. One in five incident TB cases were attributable to malnutrition, more than double the number attributed to HIV/AIDS. Like HIV/AIDS, malnutrition is a cause of secondary immunodeficiency, known as nutritionally acquired immunodeficiency syndrome (N-AIDS). However, N-AIDS remains the neglected cousin of HIV/AIDS in global TB elimination efforts.
BrainSwarming, blockchain, and bioethics: Applying engineering techniques to problems in health care and biomedicine
Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and the University of Oxford have successfully demonstrated how problem-solving techniques used in engineering, known as Innovation Enhancing Techniques, can be adapted and used to improve creativity in problem-solving when it comes to abstract problems faced in health care and biomedicine.