Over the past decades, increasing evidence has demonstrated that five retinoids, including retinol (ROL), retinol acetate (RAc), retinol propionate (RP), retinol palmitate (RPalm), and hydroxypinacolone retinoate (HPR), can be potential therapeutic agents for skin photoaging. However, therapeutic efficacies and biosafety have never been compared to these compounds.
Understanding rapid tendon regeneration in newts may one day help human athletes
A research group led by Nagoya University’s Graduate School of Engineering has uncovered how rapid tendon regeneration occurs in newts. The research, published in the Journal of Orthopaedic Research, compared the regeneration mechanism of damaged tendons in newts with those in mice. In the future, their findings could help physicians to treat human athletes recovering from tendon injuries.
Artificial intelligence used in new COVID-19 test improves accuracy
A new AI-assisted molecular diagnostic platform capable of identifying variants of COVID-19 and other infectious diseases has been developed by scientists in the UK. The low cost, portable device could play a crucial role in preventing future pandemics due to its accuracy and versatility.
Aussie babies and toddlers are targeted with unhealthy foods, finds research
Babies and toddlers can’t read or buy food yet, but new research reveals that they are being targeted with aggressive marketing in the baby and toddler aisle at the supermarket.
A long-acting biologic with transmucosal transport properties that arrest SARS-CoV-2 virus variants
When the COVID-19 pandemic first started, no effective anti-viral drugs were available to fight the disease. However, in record time, so-called monoclonal antibodies were developed as a lifesaving treatment. Now, three years later, none of the approved antibodies work effectively against the new SARS-CoV-2 virus variants due to mutations that alter their spike protein.
DNA sequencing reveals clonal evolution of tumor in childhood leukemia
Researchers at the RUDN Laboratory of Biology of Single Cells have studied the possibilities of DNA sequencing at the level of individual cells in patients with a rare form of childhood leukemia. The study revealed the mechanisms of the clonal evolution of the tumor and its transformation into a more aggressive form of leukemia at the level of individual subclones. It has also been shown that this technology can also be used as a very accurate tool for assessing the response of the disease to the treatment.
Investigating how genetic and environmental factors influence the risk and course of eating disorders
Eating disorders are debilitating conditions characterized by dysregulated eating and/or weight-control behaviors leading to significant impairment of psychosocial functioning and/or physical health. Both environmental factors and variation in multiple genetic variants influence eating disorder etiology and maintenance.
With some forms of traumatic brain injury, non-deployed vets have higher risk of epilepsy than deployed
A study of post-9/11 veterans shows that those with moderate or severe traumatic brain injury (TBI) who have never been deployed have a higher risk of epilepsy than those who have been deployed. The study is published in Neurology.
Certain migraine medications may be more effective than ibuprofen
For many people with migraine, it can be difficult to find a treatment that is effective and reliable, and information on how medications compare to one another is lacking. A new study draws data from nearly 300,000 people using a smartphone app to help people make decisions about their medications. The study found that certain migraine medications like triptans, ergots and anti-emetics may be two to five times more effective than ibuprofen for treating migraine attacks, according to new research published in Neurology.
Breaking down barriers: What happens when the vaginal microbiome attacks
Bacterial vaginosis is a common condition in which the natural microbiome of the vagina falls out of balance, sometimes leading to complications in sexual and reproductive health. But exactly how these bacterial populations disrupt vaginal health has remained unclear.