Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy. In the lab, macrophages show a lot of promise in treating cancer but so far, clinical trials have been a disappointment and biologists are trying to figure out why.
Mental health declines when becoming an unpaid caregiver, UK study finds
The mental health of people comes at a cost when they take on unpaid caring roles for friends and family. That’s according to research from St George’s, University of London and UCL which is published today in The Lancet Public Health.
Team provides new insights into HIV prevention for cisgender women
Globally speaking, most HIV infections in young women occur in poorer countries, where up to 25% of women may be infected with the HIV virus. For heterosexual women, prevention through the use of Pre-Exposure Prophylaxis (PrEP) and its active ingredients, emtricitabine/tenofovir, represents one of the few options available to protect themselves from HIV infection. Additionally, it is a very inexpensive drug, available in most resource-constrained countries.
Scientists piece together DNA repair pathway implicated in breast, ovarian and prostate cancers
Our DNA is not indestructible. Throughout the course of our lives, DNA can break in response to natural and environmental factors. Thankfully, our bodies have dedicated enzymes and pathways which can glue our broken DNA back together through several different mechanisms, known as DNA repair pathways.
Magistrate Court withdraws Bwalya Chiti’s plea
By LUCY PHIRI
LUSAKA Magistrate Sylvia Munyinya has withdrawn an entry of plea she recorded from Lusaka Lawyer, Bwalya Chiti after he informed the court that he wanted to take a fresh one in count five where is charged with conspiring to defraud government.
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Pivotal role of TLR7 protein revealed in lung disease
Researchers have revealed that the protein Toll-like receptor 7 (TLR7), usually associated with antiviral defense in the body, surprisingly, exacerbates lung conditions such as chronic obstructive pulmonary disease (COPD), also known as emphysema.
Brain fog: New study examines causes of this long-COVID symptom
Neuropsychiatric symptoms of long COVID, including brain fog, inability to concentrate, and headache, have puzzled researchers and clinicians, who are hunting for those symptoms’ causes. A new study found that neuroinflammation and blood-brain-barrier dysfunction are not likely drivers of the symptoms, giving researchers more clues in their quest to uncover what actually may be the culprit.
Study reveals link between neighborhood environmental burden and risk of cardiovascular disease
A national study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) demonstrates that neighborhood exposure to environmental hazards is significantly associated with poor cardiovascular health across the United States.
Scientists report problems with big pharma’s clinical trial data used to support FDA-approved anti-cancer medicine
A group of international scientists say they have encountered many hurdles in accessing information for a study to examine clinical trial data used to support FDA-approved anticancer medicines even when the data was classified as eligible for access and transparent sharing.
Researchers pioneer novel microfluidic method to optimize bone marrow stem cell extraction for advanced cell therapies
A research collaboration has developed a technology capable of extracting mesenchymal stem cells (MSCs) directly from pure bone marrow—also known as bone marrow aspirate (BMA), a pivotal source of MSCs—without dilution.