Resident T cells discovered in lymph nodes

The immune system is fast when it comes to fighting viruses, bacteria and other pathogens. But it also has to know when not to attack—for example, harmless substances such as pollen or house dust, which otherwise trigger allergic reactions. Regulatory T cells (Tregs) in the lymph nodes play a key role here, suppressing excessive or misdirected immune responses there.

Weekly insulin injections could be as effective in diabetes management as daily injection regimes

Insulin icodec, a once-weekly basal injection to treat type 1 diabetes, has the potential to be as effective in managing the condition as daily basal insulin treatments, according to research from the University of Surrey. The results of the year-long phase 3 clinical trial could revolutionize the future of diabetes care and help millions of people better manage their condition.

Scientists create special ‘telomouse’ with human-like telomeres

In an exciting scientific breakthrough, a team of researchers led by Professor Yehuda Tzfati from the Institute of Life Science at the Hebrew University and Professor Klaus Kaestner from the University of Pennsylvania Perelman School of Medicine, has introduced the “Telomouse.” This discovery involves changing just one tiny building block in one gene of ordinary lab mice, Mus musculus, to make their telomeres (our chromosome caps) look much more like the telomeres in humans.

Particular subgroup of antibodies responsible for dengue’s increased deadliness may lead to vaccine

Dengue fever is a viral infection with a devastating twist: those who have caught it once are more likely to develop life-threatening disease the second time around. Why our bodies not only fail to learn from prior infection but also become more vulnerable as a result is a longstanding mystery that has prevented development of a universal dengue vaccine. Rather than protecting against disease, such a vaccine could instead serve as a first exposure to prime the body for it.

Study shows that activity in the primate visual cortex is minimally linked to spontaneous movements

Many past neuroscience studies have found that animals process sensory information, such as visual stimuli, sounds, and so on, in relation to their movements within their surroundings. This experimentally confirmed idea, referred to as embodiment, has informed the present understanding of both animal and human brains, as well as the development of bio-inspired robotic systems.