Cart is empty Researchers at Baylor College of Medicine have identified a small molecule named 5D4 that can suppress the growth of breast and ovarian cancers in animal models. 5D4 works by binding to TopBP1 protein in cancer cells, disrupting its interactions with several pathways that promote cancer growth. Combining 5D4 with another cancer inhibitor, talazoparib, enhances the effectiveness of the anti-cancer activity.
New approach assesses frailty in older adults on a continuum
A national team led by a University of Pittsburgh School of Public Health epidemiologist present a new way to consider frailty: As a continuum.
Three notorious Chibolya hoodlums arrested for axing five
By NATION REPORTER
THREE people have been arrested in connection with the riot that occurred in Chibolya compound on Monday where five people were hacked by suspected criminals.
This content is locked
This is exclusive material. To read full story, click on register and choose one of the premium subscriptions to view this content. Login if you are already a premium user.
Police in Ndola probe copper concentrates theft
By ROGERS KALERO
POLICE in Ndola have launched investigations into the theft of 18 bags of copper concentrates from the Democratic Republic of Congo weighing 35.3 tonnes valued at US$85,171.31.
This content is locked
This is exclusive material. To read full story, click on register and choose one of the premium subscriptions to view this content. Login if you are already a premium user.
HIV-positive parents in Zimbabwe struggle to manage their children’s education, study finds
Over the past three decades researchers have explored various aspects of the impact of the HIV pandemic. One focus area has been children who have lost their parents to AIDS. Less attention has been given to children who are raised by parents living with HIV. This group has become much bigger as more people have access to antiretroviral therapy and are therefore expected to raise their children.
Genetic modifiers of p53 and their potential in breast cancer therapies
A new editorial perspective titled “Genetic modifiers of p53: opportunities for breast cancer therapies” has been published in Oncotarget.
Genetic link between skin tone and ancestral origin complicated by new discovery
A team of Penn State geneticists is pursuing the answers to an age-old question of human biology: the genetic origin of fundamental variations in skin pigmentation between people of different ethnicities. The link between skin pigmentation and ethnicity is more complicated than previously believed, according to new research published in the journal eLife.
Predecessors should attend national functions – HH
By NATION REPORTER
PRESIDENT Hakainde Hichilema says predecessors should be present at national functions as was the case with two surviving former Vice-Presidents Enock Kavindele and Nevers Mumba who sat with the current Vice President Mutale Nalumango during yesterday’s National Day.
This content is locked
This is exclusive material. To read full story, click on register and choose one of the premium subscriptions to view this content. Login if you are already a premium user.
How to improve performance while easing up on sprints
A new study from the University of Copenhagen demonstrates that 10-20-30 interval training is not only an effective way to improve running performance and overall health but is also just as effective for improving your running times and overall fitness, even if your sprints are only at 80%. The researchers hope that the new knowledge can encourage more people to adopt this type of training, which benefits both blood pressure and cholesterol levels.
Doctors’ group expands definition of ‘infertility’
A new, more inclusive definition of infertility has been crafted by the American Society for Reproductive Medicine (ASRM).