Neuronal activity shapes the development of astrocytes, shows study

Researchers at Baylor College of Medicine have unraveled the processes that give astrocytes, the most abundant glial cell in the brain, their special bushy shape, which is fundamental for brain function. They report in the journal Nature that neuronal activity is necessary and sufficient for astrocytes to develop their complex shape, and interrupting this developmental process results in disrupted brain function.

Randomized clinical trial shows reduction in surgical site infections

The first-ever randomized clinical trial linked to registry data from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) shows that for patients undergoing pancreatoduodenectomy, also known as the Whipple procedure, a change in antibiotics before the procedure reduces the rate of surgical site infections (SSIs). The findings were published recently in the Journal of the American Medical Association (JAMA).